摘要
目的:探讨冠心宁联合常规西药治疗冠心病心血瘀阻证的效果。方法:选取2024年1—12月杭州市西湖区转塘街道社区卫生服务中心收治的冠心病心血瘀阻证患者100例作为研究对象,采用随机数字表法分为常规组与试验组,各50例。常规组采用常规西药治疗,试验组在常规组基础上给予冠心宁治疗。比较两组治疗效果。结果:治疗后,两组胸痛或胸闷、痛引肩背或臂内侧、心悸不宁、口唇紫暗评分降低,且试验组低于常规组(P<0.001)。试验组治疗总有效率高于常规组(P=0.014)。治疗后,两组全血高切黏度、全血低切黏度、血小板聚集指数、红细胞聚集指数降低,且试验组低于常规组(P<0.001)。两组不良反应总发生率比较,无统计学差异(P>0.05)。结论:冠心宁联合常规西药治疗冠心病心血瘀阻证的效果显著,可缓解患者临床症状,改善血液流变学指标,且用药安全性较高。
Objective:To investigate the effect of Guanxinning combined with conventional western medicine in treatment of coronary heart disease with syndrome of stagnant blockade of heart blood.Methods:From January 2024 to December 2024,a total of 100 patients with coronary heart disease with syndrome of stagnant blockade of heart blood who were admitted to Hangzhou City Xihu District Zhuantang Subdistrict Community Health Service Center were selected as the study subjects.According to the random number table method,they were divided into the conventional group and the experimental group,with 50 cases in each group.The conventional group was treated with conventional western medicine,and the experimental group was treated with Guanxinning on the basis of the conventional group.The therapeutic effects were compared between the two groups.Results:After treatment,the scores of chest pain or chest tightness,pain caused by shoulder and back or inner arm,palpitation,and dark purple oral lips in the two groups decreased,and the scores in the experimental group were lower than those in the conventional group(P<0.001).The overall response rate of treatment in the experimental group was higher than that in the conventional group(P=0.014).After treatment,the whole blood high shear viscosity,whole blood low shear viscosity,platelet aggregation index and red blood cell aggregation index in the two groups decreased,and these parameters in the experimental group were lower than those in the conventional group(P<0.001).There was no statistical difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:Guanxinning combined with conventional western medicine has a significant effect in the treatment of coronary heart disease with syndrome of stagnant blockade of heart blood,and can relieve the clinical symptoms of patients,improve hemorheological indicators,and maintain high medication safety.
作者
廖洪恢
李瑞
樊莉
杨晓意
金建弟
Liao Honghui;Li Rui;Fan Li;Yang Xiaoyi;Jin Jiandi(Hangzhou City Xihu District Zhuantang Subdistrict Community Health Service Center,Hangzhou 310024,Zhejiang Province,China)
出处
《中国社区医师》
2025年第31期46-48,共3页
Chinese Community Doctors
基金
浙江省医学会临床医学专项资金项目(编号:2023ZYC-A130)。
关键词
冠心病
心血瘀阻
冠心宁
阿司匹林
琥珀酸美托洛尔
阿托伐他汀钙
硝酸甘油
Coronary heart disease
Stagnant blockade of heart blood
Guanxinning
Aspirin
Metoprolol succinate
Atorvastatin calcium
Nitroglycerin
