摘要
目的分析先兆早产住院患者应用硫酸镁治疗的效果。方法选取先兆早产患者60例,应用随机抽签法分为对照组(n=30,给予常规疗法治疗)及观察组(n=30,在对照组基础上给予硫酸镁治疗)。比较两组患者的生命体征、临床指标、不良母婴结局以及用药不良反应发生情况。结果治疗后,观察组患者收缩压(105.29±3.68)mm Hg(1 mm Hg=0.133 kPa)、舒张压(68.27±3.45)mm Hg和心率(80.14±3.15)次/min均低于对照组的(112.48±3.51)mm Hg、(72.76±3.30)mm Hg、(85.62±3.07)次/min(P<0.05)。观察组患者症状消失时间(45.62±7.38)h、宫缩消失时间(7.34±1.27)h均短于对照组的(64.65±7.24)、(10.28±1.54)h,妊娠延长时间(21.08±2.34)d长于对照组的(17.26±2.17)d,新生儿出生1 min Apgar评分(8.46±0.85)分高于对照组的(7.34±0.72)分(P<0.05)。结论在先兆早产住院患者治疗中应用硫酸镁能够改善患者临床症状,有效控制患者血压和心率,降低产后出血、新生儿呼吸窘迫、新生儿脑瘫等的发生率,改善母婴结局;同时,治疗期间患者不良反应发生率低,治疗安全性高。
Objective To analyze the efficacy of magnesium sulfate in hospitalized patients with threatened preterm labor.Methods 60 patients with threatened preterm labor were selected and assigned to a control group(n=30,received conventional treatment),and an observation group(n=30,received magnesium sulfate in addition to the control group)according to random lottery method.The vital signs,clinical indicators,adverse maternal and infant outcomes,and adverse drug reactions were compared between the two groups.Results After treatment,the systolic blood pressure(105.29±3.68)mm Hg(1 mm Hg=0.133 kPa),diastolic blood pressure(68.27±3.45)mm Hg and heart rate(80.14±3.15)beats/min of the observation group were lower than those of the control group[(112.48±3.51)mm Hg,(72.76±3.30)mm Hg and(85.62±3.07)beats/min](P<0.05).The symptom disappearance time(45.62±7.38)h and uterine contraction disappearance time(7.34±1.27)h of the observation group were shorter than those of the control group[(64.65±7.24)and(10.28±1.54)h];the prolonged pregnancy time(21.08±2.34)d was longer than the control group's(17.26±2.17)d,and the 1-min Apgar score of the newborn(8.46±0.85)points was higher than the control group's(7.34±0.72)points(P<0.05).Conclusion In the treatment of hospitalized patients with threatened premature labor,magnesium sulfate therapy can improve clinical symptoms,effectively control blood pressure and heart rate,reduce the incidence of postpartum hemorrhage,neonatal respiratory distress,and neonatal cerebral palsy,and improve maternal and infant outcomes.Furthermore,the incidence of adverse reactions during treatment was low,indicating a high safety profile.
作者
戴晓霞
曾思浅
DAI Xiao-xia;ZENG Si-qian(Department of Obstetrics and Gynecology,Huizhou Zhongda Huiya Hospital(Hui Ya Hospital of the First Affiliated Hospital of Sun Yat-sen University),Huizhou 516081,China)
出处
《中国实用医药》
2026年第3期116-119,共4页
China Practical Medicine
关键词
硫酸镁
先兆早产
生命体征
临床症状
不良母婴结局
不良反应
Magnesium sulfate
Threatened preterm labor
Vital signs
Clinical symptoms
Adverse maternal and infant outcomes
Adverse reactions
