摘要
目的探讨结直肠癌造口患者发生造口周围潮湿相关性皮肤损伤(PMASD)的影响因素。方法选取80例结直肠癌造口患者为研究对象。均评估PMASD发生情况,以此分为PMASD组与非PMASD组,收集患者年龄、性别、合并高血压、合并糖尿病、放疗史、造口开口高度、造口种类、应用防漏膏、营养状况、排便情况等多方面基础资料,开展Logistic回归分析,获得影响PMASD发生的危险因素。结果80例患者共31例出现PMASD,发生率为38.75%(31/80);单因素显示,年龄、合并糖尿病、放疗史、造口开口高度、应用防漏膏、营养状况与PMASD发生关系密切,有统计学差异(P<0.05);多因素显示,年龄≥60岁(OR=2.871,95%置信区间=1.129~7.302)、合并糖尿病(OR=6.175,95%置信区间=2.266~16.827)、放疗史(OR=3.239,95%置信区间=1.224~8.568)、造口开口高度平于或低于皮肤表面(OR=3.363,95%置信区间=1.300~8.695)、未应用防漏膏(OR=3.239,95%置信区间=1.224~8.568)、营养不良(OR=3.138,95%置信区间=1.230~8.010)为影响结直肠癌造口患者发生PMASD的危险因素(P<0.05且OR>1)。结论结直肠癌造口患者发生PMASD与年龄≥60岁、合并糖尿病、放疗史、造口开口高度平于或低于皮肤表面、未应用防漏膏、营养不良有关,还需高度重视,做好针对性防治。
Objective To investigate the influencing factors of peristomy moisture-related skin injury(PMASD)in patients with colorectal cancer.Methods 80 patients with colostomy were selected as the study objects.The occurrence of PMASD was evaluated and divided into PMASD group and non-PMASD group.The patients'age,gender,combined hypertension,combined diabetes,history of radiotherapy,height of stoma opening,type of stoma,application of leak-prevention cream,nutritional status,defecation and other basic data were collected,and Logistic regression analysis was carried out.The risk factors affecting the occurrence of PMASD were obtained.Results There were 31 cases of PMASD in 80 patients,the incidence was 38.75%(31/80).Single factors showed that age,diabetes mellitus,history of radiotherapy,height of stomatostomy opening,application of leak prevention cream and nutritional status were closely related to the occurrence of PMASD,with statistical differences(P<0.05).Multivariate results showed that age≥60 years old(OR=2.871,95%CI=1.129~7.302),combined diabetes(OR=6.175,95%CI=2.266~16.827),radiotherapy history(OR=3.239,95%confidence interval=1.224~8.568),the height of the stomostomy opening was at OR below the skin surface(OR=3.363,95%confidence interval=1.300~8.695),no leakage cream was applied(OR=3.239,95%confidence interval=1.224~8.568),malnutrition(OR=3.138,95%confidence interval=1.230~8.010)were risk factors for PMASD in patients with colorectal cancer stomy(P<0.05 and OR>1).Conclusion The occurrence of PMASD in patients with colorectal cancer stomy is related to age≥60 years old,diabetes mellitus,history of radiotherapy,the height of the stomy opening is at or below the skin surface,no application of leak prevention cream,and malnutrition,which should be paid more attention to and targeted prevention and treatment.
作者
杨皓月
张萌萌
杨舒涵
YANG Haoyue;ZHANG Mengmeng;YANG Shuhan(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)
出处
《实用癌症杂志》
2025年第12期2005-2008,共4页
The Practical Journal of Cancer
基金
河南省医学科技攻关计划项目(编号:LHGJ20220969)。
关键词
结直肠癌
造口周围潮湿相关性皮肤损伤
影响因素
年龄
Colorectal cancer
Moisture-related skin injury around the stoma
Influencing factors
Age
