摘要
Natural biomolecular structures possess an inherent ability to encode chiral conformations,thus the generation and regulation of chiroptical activity is crucial.While artificial polymers hold special significance in understanding life's origins,the fundamental connections between the racemic architecture and functional characteristics still need to be fully investigated.Herein,this study reports the generation and regulation of the global chirality and helical sense in racemic polymer systems,focusing on the synergistic effects of liquid crystallinity(LC)and solvophobic interaction.By systematically varying the length of alkyl spacers and the degree of polymerization(DP)of the core-forming azobenzene(Azo)blocks,the chiral communications,morphological transitions and chiroptical properties of the racemic nanoaggregates can be precisely controlled.Furthermore,the proposed“first come,first serve”(FF)and the“late-comer lives above”(LA)effect are broadly applicable and are expected to be applied to various types of racemic polymer systems.This work provides valuable insights into the design of self-assembled systems with tunable global chirality and morphology,thereby advancing the understanding of the origins of homochirality in nature.
基金
support from the National Natural Science Foundation of China(22301208,92356305)
Natural Science Foundation of Anhui Province(2308085J15)
Natural Science Foundation of Anhui Provincial Higher Education Institutions(2023AH010012)
Natural Science Foundation of Jiangsu Province(BK20230505)
Jiangsu Funding Program for Excellent Postdoctoral Talent,Key Laboratory of Polymeric Material Design and Synthesis for Biomedical Function,the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions,Program of Innovative Research Team of Soochow University and Postgraduate Research&Practice Innovation Program of Jiangsu Province.
