摘要
近视已经成为全球性的公共问题,我国的近视发病年龄与程度整体呈现低龄化与高度化的特征。近年来,低强度红光干预作为一种新兴方法,为青少年近视防控提供了新的思路。国内多项临床试验证实,LLRL疗法能有效抑制儿童眼轴增长、延缓近视进展,并显示出预防近视发生的潜力。目前,其作用机制尚未完全明确,可能涉及增加脉络膜血流、改善巩膜缺氧、光照促进视网膜多巴胺分泌等因素。本文旨在综述LLRL疗法在近视防控中的临床有效性、安全性、影响因素、对眼部参数的影响及其潜在作用机制的研究进展。
Myopia has emerged as a global public health challenge,with China exhibiting a concerning trend of younger age of onset and higher prevalence of high myopia.In recent years,Low-Level Red Light(LLRL)therapy has become an innovative intervention,offering new prospects for myopia prevention and control among children and adolescents.Multiple clinical trials conducted in China have demonstrated that LLRL therapy effectively enhances axial elongation,slows myopia progression,and shows potential in preventing myopia onset among children and adolescents.Although the precise mechanisms of action remain incompletely understood,they may involve increased choroidal blood flow,amelioration of scleral hypoxia,and light-stimulated retinal dopamine secretion.This review aims to summarize recent research advances regarding the clinical efficacy,safety,influencing factors,ocular parameter impacts,and potential mechanisms of LLRL therapy for myopia prevention and control.
作者
李琳
廖娅
王小娟
LI Lin;LIAO Ya;WANG Xijua(Xuzhou Municipal Hospital Affiliated to Xuzhou Medical University,Xuzhou 221100,Jiangsu,China;Xuzhou Medical University,Xuzhou 221004,Jiangsu,China;Shanghai General Hospital Affiliated to Shanghai Jiao Tong University,Shanghai 200080,China)
出处
《中国校医》
2025年第8期592-596,614,共6页
Chinese Journal of School Doctor
基金
徐州医学领军人才培养项目(XWRCHT20210022)
江苏大学医教协同创新基金(JDYY2023117)。
关键词
近视
低强度红光
儿童
青少年
Myopia
Low-Level Red Light(LLRL)
Children
Adolescent
