摘要
随着人们生活水平的提高和对自身健康的关注,保健食品需求量日益增加,市场规模不断扩大,给相关部门带来了许多监管难题。保健食品中非法添加药物问题严重威胁消费者身体健康,是影响保健食品产业可持续发展的重要因素,因此亟需建立完善保健食品中非法添加药物检测方法和监管体系。其中,缓解体力疲劳类保健食品通常被宣传为具有壮阳或补脑功能,许多不法商贩通过非法添加磷酸二酯酶5型抑制剂或合成类促智药物来增强其声称功效。本文总结了壮阳和补脑两类缓解体力疲劳保健食品中非法添加药物种类、危害及非法添加现状,综述了液相色谱、液相色谱质谱联用、光谱、免疫分析、电化学分析等技术在两类保健食品非法添加药物检测研究中的最新进展,以期为公安机关及相关监管部门的检测工作提供参考。
With the improvement of living standards and an increasing awareness of personal health,the demand for health foods has surged.Consequently,the market has expanded continuously,presenting numerous regulatory challenges for the relevant authorities.The illegal addition of drugs in health foods poses a significant threat to consumer health and impedes the sustainable development of the health foods industry.Therefore,it is imperative to establish comprehensive methods for detecting these unlawful substances in health foods and to develop robust regulatory systems.Among these,health foods that claim to relieve physical fatigue are particularly vulnerable to such illegal adulterations,which primarily fall into two categories.The first is often marketed with alleged aphrodisiac or sexual enhancement benefits,while the second claims to improve cognitive function.Many unscrupulous vendors illegally add phosphodiesterase 5 inhibitors(PDE5i)or synthetic nootropics to enhance these claimed benefits.This paper provides a summary of the types,hazards,and prevalence of illicit drug additives in health foods designed for aphrodisiac or cognitive improvement,and gives an overview of the latest advancements in detection methodologies,including high-performance liquid chromatography(HPLC),liquid chromatography-mass spectrometry(LC-MS),spectroscopy,immunoassays,and electrochemical analysis.The primary methods for detecting illegal drug additives in aphrodisiac health foods include HPLC,LC-MS,spectroscopy,mass spectrometry(MS),immunoassay,and electrochemical analysis.For brain-tonifying health foods,the main detection methods are HPLC and LC-MS.Finally,this article explores the future of detecting illicit drug additives in health foods from the perspectives of standardizing preprocessing methods,expanding the application of portable instruments,employing various techniques for non-targeted screening,and utilizing artificial intelligence and machine learning technologies.The intent of this paper is to offer valuable insights and reference for law enforcement and regulatory agencies in the pursuit of monitoring and ensuring the safety of these health foods.
作者
李玉静
栾玉静
何洪源
周志刚
LI Yujing;LUAN Yujing;HE Hongyuan;ZHOU Zhigang(Beijing Key Laboratory of Forensic Science,People’s Public Security University of China,Beijing 100038,China;School of Criminal Investigation,People’s Public Security University of China,Beijing 100038,China;Institute of Forensic Science,Ministry of Public Security,Beijing 100038,China;Institute of Criminal Science and Technology of Zhoushan Public Security Bureau,Zhoushan 316013,Zhejiang,China)
出处
《刑事技术》
2025年第6期627-634,共8页
Forensic Science and Technology
基金
中央公益性基金基本科研业务费(2023JBGS03)
北京市现场物证检验工程技术研究中心开放课题(2023CSEEKFKT008)
刑事科学技术北京市重点实验室建设项目(2023ZB06)。
