摘要
针对斑重唇鱼仔鱼的细菌性疾病、寄生虫病、烂鳃、腐皮病及水霉病,分别以甲醛、食盐、聚维酮碘、苯扎溴铵及亚甲基蓝对体质量(96.23±6.03)mg斑重唇鱼仔鱼的96 h急性毒性进行试验,评价药物的安全浓度。结果表明:甲醛对斑重唇鱼仔鱼的96 h半致死质量浓度为65.05 mg/L,急性毒性为中毒;食盐对仔鱼的96 h半致死质量浓度为11590.12 mg/L,急性毒性为低毒;聚维酮碘对仔鱼的96 h半致死质量浓度为28.60 mg/L,急性毒性为高毒;苯扎溴铵对仔鱼的96 h半致死质量浓度为1.10 mg/L,急性毒性为极高毒;亚甲基蓝对仔鱼的96 h半致死质量浓度为18.74 mg/L,急性毒性为高毒,其安全质量浓度分别为13.06 mg/L、3412.65 mg/L、7.25 mg/L、0.20 mg/L和4.79 mg/L。5种药物对斑重唇鱼仔鱼的敏感性为苯扎溴铵>亚甲基蓝>聚维酮碘>甲醛>食盐。苯扎溴铵毒性最强,亚甲基蓝及聚维酮碘次之,甲醛及食盐毒性最弱。
This study conducted 96-hour acute toxicity tests on Diptychus maculates Steindachner(mean body mass:96.23 mg±6.03 mg)to determine the safety thresholds for commonly used aquaculture drugs:formaldehyde,sodium chloride,povidone-iodine,benzalkonium bromide and methylene blue.These therapeutics are frequently applied in the treatment of bacterial and parasitic infections,gill rot,dermatosis,and saprolegniasis.The 96-h median lethal concentration(LC_(50))values were 65.05 mg/L(moderate toxicity)for formaldehyde,11590.12 mg/L(low toxicity)for sodium chloride,28.60 mg/L(high toxicity)for povidone-iodine,1.10 mg/L(extreme toxicity)for benzalkonium bromide,and 18.74 mg/L(high toxicity)for methylene blue.The corresponding safety concentrations were calculated as 13.06 mg/L,3412.65 mg/L,7.25 mg/L,0.20 mg/L and 4.79 mg/L,respectively.Sensitivity of D.maculatus larvae to these drugs decreased in the following order:benzalkonium bromide>methylene blue>povidone-iodine>formaldehyde>sodium chloride.Among these,benzalkonium bromide exhibited the highest toxicity,followed by methylene blue and povidoneiodine,while formaldehyde and sodium chloride showed comparatively lower toxicity.
作者
张涛
胡江伟
米乃瓦尔·木依提
沙文军
高广扩
杨博文
蔡林钢
牛建功
ZHANG Tao;HU Jiangwei;MINAWAER·Muyiti;SHA Wenjun;GAO Guangkuo;YANG Bowen;CAI Lingang;NIU Jiangong(Xinjiang Uygur Autonomous Region Aquatic Development Center(Xinjiang Uygur Autonomous Region Fishery Research Institute),Scientific Observing and Experimental Station of the Northwest Region,Urumqi 830000,China;National Energy Group Xinjiang Jilintai Hydropower Development Co.Ltd,Yili Xinjiang 835000,China)
出处
《西北农业学报》
北大核心
2025年第11期1975-1982,共8页
Acta Agriculturae Boreali-occidentalis Sinica
基金
新疆自然科学基金(2023D01A114)。
关键词
水产药物
斑重唇鱼
急性毒性
安全浓度
Aquatic drugs
Diptychus maculatus Steindachner
Acute toxicity
Safe concentrations
