摘要
带状疱疹后遗神经痛(PHN)和神经性皮炎(ND)均以疼痛或瘙痒为主要表现,且两者发病机制均涉及肝气郁结、气血不足和脉络瘀阻。由于PHN和ND核心病机的一致性,基于“异病同治”理论,围绕肝脾功能失调、气血失和与络脉不通的动态关系,提出了整合治疗方案:使用疏肝健脾、调和气血的中药复方内服治疗,常配合虫类与藤类药物;同时运用火针、刺络拔罐等方法疏通脉络的外部治疗,以协同缓解疼痛和瘙痒症状。未来,还需要采用多中心临床试验评估以上整合方案的疗效,并运用代谢组学和人工智能技术,深入分析肝脾、气血、络脉之间相互作用的分子调控机制。
Postherpetic neuralgia(PHN)and neurodermatitis(ND)both present with pain or itching as the main manifestations,and the pathogenesis of both involves liver qi stagnation,insufficiency of qi and blood,and blood stasis in the meridians.Due to the consistency of the core pathogenesis of PHN and ND,based on the theory of"treating different diseases with the same therapy",an integrated treatment plan was proposed,focusing on the dynamic relationship between liver and spleen dysfunction,disharmony of qi and blood and blocked meridians:internal administration of a traditional Chinese medicine compound that can soothe the liver,strengthen the spleen,and harmonize qi and blood,often in combination with insect and vine drugs;external treatments such as fire needle and bloodletting and cupping to unblock the meridians to relieve pain and itching symptoms in a coordinated manner.In the future,multi-center clinical trials will be needed to evaluate the efficacy of the above-mentioned integrated plan,and metabolomics and artificial intelligence technologies will be applied to deeply analyze the molecular regulatory mechanisms of the interactions among the liver and spleen,qi and blood,and meridians.
作者
罗瑾
蔡靓羽
LUO Jin;CAI Liangyu(Graduate School of Nanjing University of Chinese Medicine,Nanjing 210023,China;Department of Pain Management,Wuxi Hospital Affiliated to Nanjing University of Chinese Medicine,Wuxi 214071,China)
出处
《医学综述》
2025年第20期2531-2536,共6页
Medical Recapitulate
基金
江苏省中医药科技发展计划项目(MS2022057)。
关键词
带状疱疹后遗神经痛
神经性皮炎
异病同治
Postherpetic neuralgia
Neurodermatitis
Same treatment for different diseases
