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胫骨远端恶性肿瘤的保肢治疗研究

Limb-sparing treatment of malignant tumors of the distal tibia
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摘要 胫骨远端原发性恶性肿瘤发病率较其它部位更低,且这类患者发生的转移率和病死率也更低[1]。对于发生在该部位的恶性及潜在恶性肿瘤,由于软组织覆盖范围的限制和膝下假肢令人满意的功能[2],膝关节下截肢一直是标准的手术方法[3]。尽管膝以下截肢者的功能评分可能达到90%或更高,但有些患者出于心理或社会原因拒绝截肢[4]。 Malignant tumors occurring in the distal tibia are extremely rare,mainly including osteosarcoma and Ewing's sarcoma.Due to the difficulty in soft tissue coverage of this area and the satisfactory functional outcomes of below-knee prostheses,amputation has been the standard surgical procedure traditionally.However,with the advent of neoadjuvant chemotherapy,advancements in imaging techniques,improvements in surgical technology,and increased psychological acceptance among patients,the majority now opt for limb-salvage treatment.Nevertheless,the challenges of reconstructing bone and soft tissue after extensive resection are significant because of the difficulties in soft tissue coverage,high risks of infection,and wound-related complications in this region.Due to the low incidence,limited literature is available,resulting in ongoing debates regarding treatment strategies.This review provides a literature-based overview and discussion of various limb-salvage reconstruction methods.
作者 林艺镇 张智长 LIN Yi-zhen;ZHANG Zhi-chang(Department of Orthopedics,the Sixth People's Hospital Affiliated to Shanghai Jiao Tong University,Shanghai,200000,China)
出处 《中国骨与关节杂志》 2025年第11期1051-1056,共6页 Chinese Journal of Bone and Joint
关键词 胫骨 肿瘤 骨肉瘤 肉瘤 EWING 假体植入 保肢 综述 Tibia Neoplasms Osteosarcoma Ewing sarcoma,Ewing Prosthesis implantation Limb-salvage Review
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