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肠菌移植技术管理的天津专家共识(2025版)

Tianjin expert consensus on the management of intestinal fecal microbiota transplantation(2025 edition)
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摘要 肠菌移植(FMT)是一种以肠道菌群为靶点进行疾病干预的新型医疗技术,为多种肠内外疑难病症提供了创新性治疗方案,突破了传统疗法在部分疾病中的疗效局限。目前,该技术在我国多个地区已形成成熟的应用体系,但天津地区的临床实践仍需规范管理。随着FMT研究的快速推进,洗涤菌群移植、供受体精准配型、疗效智能预测评估等创新策略不断涌现,推动其向标准化及精准化方向纵深发展。在此背景下,为促进FMT在本地区的应用发展,天津市消化质量控制委员会组织专家,基于2022及2023版专家共识,结合地区医疗实践特点,制定了本共识。本共识系统梳理了FMT技术各环节的管理要求,并从技术操作标准化建设与临床应用创新拓展两个维度提出15条针对性建议,旨在为天津地区FMT的诊疗推广提供科学规范的实践指引。 Fecal microbiota transplantation(FMT)is a novel medical technology targeting gut microbiota for disease intervention.It offers innovative treatment strategies for various intestinal and extraintestinal refractory disorders,overcoming the therapeutic limitation of traditional therapies in certain diseases.Currently,FMT has established mature application systems in multiple regions of China,but its clinical practice within Tianjin area still needs to be standardized and managed.With the rapid advancement of FMT research,innovative strategies such as washed microbiota transplantation(WMT),donor-recipient precision matching and intelligent predictive assessment of efficacy have emerged,driving its in-depth development towards standardization and precision.Against this backdrop,in order to promote the application and development of FMT in this region,Tianjin Digestive Quality Control Committee organized experts to develop the“Tianjin Expert Consensus on the Management of Fecal Microbiota Transplantation”based on the 2022 and 2023 expert consensus standards and integrate the characteristics of regional medical practices.The consensus systematically addresses the management requirements for all aspects of FMT technology.It proposes 15 targeted recommendations from two dimensions:standardization of technical operations and innovative expansion of clinical applications.The goal is to provide scientific and standardized practical guidelines for promoting FMT diagnosis and treatment in Tianjin.
作者 天津市消化质量控制委员会 王邦茂 夏时海 曹海龙 辛风然 赵锟 Tianjin Digestive Quality Control Committee
出处 《天津医药》 2025年第11期1121-1130,共10页 Tianjin Medical Journal
关键词 肠菌移植 临床实践 标准化 管理 共识 fecal microbiota transplantation clinical practice standardization management consensus
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