摘要
目的 观察安宫牛黄丸联合针灸治疗儿童中重度颅脑创伤(TBI)的临床效果。方法 选取2022年1月至2023年1月江西省儿童医院收治的81例中重度TBI患儿作为研究对象,按照随机数字表法分为对照组(27例)、试验A组(27例)和试验B组(27例)。对照组予以常规内科治疗及外科手术治疗;试验A组在对照组方法的基础上联合安宫牛黄丸治疗;试验B组在试验A组方法的基础上联合针灸治疗。比较三组的格拉斯哥昏迷评分(GCS)、有创呼吸机使用情况,以及预后。结果 共78例患儿完成干预,其中对照组25例,试验A组26例,试验B组27例。干预5、10 d,试验A组、试验B组的GCS评分均高于对照组,差异有统计学意义(P<0.05);但试验A组、试验B组干预5、10 d的GCS评分比较,差异无统计学意义(P>0.05)。试验A组、试验B组的有创呼吸机使用天数短于对照组,差异有统计学意义(P<0.05);但试验A组、试验B组的使用天数比较,差异无统计学意义(P>0.05)。出院时、随访6个月时,试验A组与试验B组的预后良好比例高于对照组,试验B组的预后良好比例高于试验A组,差异有统计学意义(P<0.017)。结论 安宫牛黄丸联合针灸治疗TBI患儿临床获益显著,能改善预后并降低患儿病死风险,建议临床推广应用。
Objective To observe the clinical effect of Angong Niuhuang Pills combined with acupuncture in the treatment of children with moderate-severe traumatic brain injury(TBI).Methods A total of 81 children with moderate to severe TBI admitted to Jiangxi Provincial Children's Hospital from January 2022 to January 2023 were selected as the research objects.According to the random number table method,they were divided into control group(27 cases),experimental group A(27 cases)and experimental group B(27 cases).The control group was given routine medical treatment and surgical treatment,the experimental group A was treated with Angong Niuhuang Pills on the basis of the control group,and the experimental group B was treated with acupuncture on the basis of experimental group A.The Glasgow coma scale(GCS),use of invasive ventilator,and prognosis were compared among the three groups.Results A total of 78 children completed the intervention,including 25 cases in the control group,26 cases in the experimental group A and 27 cases in the experimental group B.After 5 and 10 days of intervention,the GCS scores of experimental group A and experimental group B were higher than those of the control group,and the differences were statistically significant(P<0.05).However,there was no significant difference in GCS scores between experimental group A and experimental group B after 5 and 10 days of intervention(P>0.05).The days of invasive ventilator use in experimental group A and experimental group B were shorter than those in the control group,and the differences were statistically significant(P<0.05).However,there was no statistically significant difference in the number of days of use between experimental group A and experimental group B(P>0.05).At discharge and 6 months of follow-up,the proportion of good prognosis in experimental group A and experimental group B were higher than that in control group,and the proportion of good prognosis in experimental group B was higher than that in experimental group A,and the differences were statistically significant(P<0.017).Conclusion Angong Niuhuang Pills combined with acupuncture has significant clinical benefits in the treatment of TBI children,which can improve the prognosis and reduce the risk of death in children,and is recommended for clinical application.
作者
陈媛媛
余婧
高琦
朱友荣
CHEN Yuanyuan;YU Jing;GAO Qi;ZHU Yourong(Pediatric Intensive Care Unit,Jiangxi Provincial Children's Hospital,Jiangxi Province,Nanchang 330000,China)
出处
《中国当代医药》
2025年第19期68-71,共4页
China Modern Medicine
基金
江西省中医药管理局科技计划项目(2022A075)
关键词
安宫牛黄丸
针灸
儿童
颅脑创伤
临床效果
Angong Niuhuang Pills
Acupuncture
Children
Traumatic brain injury
Clinical effect
