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基于清晰集定性比较分析的医院感染暴发事件危险因素的多组态路径分析

Multi-configurational pathway analysis on risk factors for healthcare-associated infection outbreak events based on crisp-set qualitative comparative analysis
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摘要 目的医院感染暴发事件对医疗领域构成重大威胁。本文旨在提供一种新视角,解释医院感染暴发事件因果路径,并寻求有效预防和控制策略。方法采用文献研究法收集医院感染暴发事件案例,运用清晰集定性比较分析探讨危险因素之间的相互作用。结果消毒、隔离、手卫生、管理和制度不到位以及抗菌药物使用不合理、进行侵入性操作、患者免疫功能低下是医院感染暴发事件的前因。组态分析揭示医院感染暴发事件与危险因素之间存在四条路径,归纳为隔管协同型和多因共促型两种类型。结论预防和控制医院感染暴发应注意人员隔离(包括患者隔离和医务人员防护)与管理的协同作用,做好消毒和隔离工作,合理使用抗菌药物,防止危险因素组合导致感染暴发。 Objective Healthcare-associated infection(HAI)outbreak events pose significant threat to healthcare system.This paper aims to provide a new perspective to explain the causal pathways of HAI outbreak events and seek effective prevention and control strategies.Methods Cases of HAI outbreak events were collected by literature review.Interaction among risk factors was explored through crisp-set qualitative comparative analysis(csQCA).Results Inadequate procedures such as disinfection,isolation,hand hygiene,and management system,as well as improper use of antimicrobial agents,invasive procedures,and low immune function of patients were the antece-dents of HAI outbreak events.Configuration analysis reveals that there were four pathways between HAI outbreak events and risk factors,and could be classified into two types:the isolation-management synergistic type and multi-factor co-promotion type.Conclusion Prevention and control of HAI outbreak requires coordinated effect of personnel isolation(including isolation of patients and protection of healthcare workers)and management,proper disinfection and isolation,and rational use of antimicrobial agents,so as to prevent infection outbreaks caused by the combination of risk factors.
作者 于冰艳 宁宁 张璐澔 齐越 YU Bingyan;NING Ning;ZHANG Luhao;QI Yue(Department of Social Medicine Teaching and Research,School of Health Management,Harbin Medical University,Harbin 150081,China)
出处 《中国感染控制杂志》 北大核心 2025年第10期1377-1381,共5页 Chinese Journal of Infection Control
基金 国家自然科学基金面上项目(72474062)。
关键词 医院感染暴发 危险因素 清晰集定性比较分析 healthcare-associated infection outbreak risk factor crisp-set qualitative comparative analysis
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