摘要
动脉粥样硬化是最常见的心血管系统疾病,血脂异常是导致动脉粥样硬化的首要危险因素。21世纪以来,我国动脉粥样硬化发病率仍呈上升趋势,临床治疗策略亟需优化。研究发现降低胆固醇和减轻炎症反应不仅可以稳定斑块,甚至可以逆转斑块。随着影像学技术的发展,越来越多的方法可以用于评估斑块的分布和负荷,进一步指导调整临床降脂策略。本文对单用他汀类药物以及联合降脂策略的临床应用效果及最新研究进展进行综述。
Atherosclerosis is the most common cardiovascular disease,and dyslipidemia is the primary risk factor leading to atherosclerosis.Since the 21st century,the incidence rate of atherosclerosis in China is still on the rise,and the clinical treatment strategies of its patients need to be optimized urgently.Related studies have found that reducing cholesterol and alleviating inflammation can not only stabilize plaques,but also reverse them.With the development of imaging technology,more and more methods can be used to evaluate the distribution and burden of plaques,further guiding the adjustment of clinical lipid-lowering strategies.This article reviews the clinical application effects and latest research progress of monotherapy with statins and combined lipid-lowering strategies.
作者
康瑞龙
邓勇志
Kang Ruilong;Deng Yongzhi(Department of Cardiovascular Surgery,the Affiliated Hospital of Shanxi Medical University,Shanxi Cardiovascular Hospital(Institute),Shanxi Clinical Medical Research Center for Cardiovascular Disease,Taiyuan 030024,China)
出处
《中华胸心血管外科杂志》
2025年第9期570-576,共7页
Chinese Journal of Thoracic and Cardiovascular Surgery
