摘要
冠状动脉粥样硬化斑块形成是冠心病的病理基础,贯穿疾病发生与进展的整个过程。近年来国内外大量关于动脉粥样硬化的研究证实,降脂治疗不仅能稳定斑块,甚至能“逆转斑块”。本文对冠状动脉粥样硬化斑块逆转的机制、临床证据、治疗策略的最新研究进展进行概述。
The formation of coronary atherosclerotic plaque is an important pathological basis for coronary heart disease,which runs through the overall process of the formation and progression of the disease.In recent years,a large number of studies on atherosclerosis at home and abroad have confirmed that lipid-lowering therapy can not only stabilize plaque,but also"reverse plaque".This article reviews the research progress of the mechanism,clinical evidence and treatment strategies of coronary atherosclerotic plaque regression.
作者
陈倍佳
洪李锋
李建军
CHEN Beijia;HONG Lifeng;LI Jianjun(Department of Cardiology,The Fifth Hospital in Wuhan,Wuhan 430050,China;National Center for Cardiovascular Diseases,Fuwai Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100037,China)
出处
《中国分子心脏病学杂志》
CAS
2022年第5期4873-4877,共5页
Molecular Cardiology of China
基金
武汉市科技计划项目(2020020601012315)。
关键词
冠状动脉疾病
动脉粥样硬化
斑块逆转
Coronary artery disease
Atherosclerosis
Plaque regression
