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胎膜早破合并绒毛膜羊膜炎与不良妊娠结局的研究进展

Research Progress on Adverse Pregnancy Outcomes with Premature Rupture of Membranes and Chorioamnionitis
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摘要 胎膜早破(PROM)是一种妊娠期常见的并发症,与其相关的主要风险之一是绒毛膜羊膜炎(CA)。PROM合并CA会引起胎儿炎症反应综合征,增加新生儿感染性疾病和围产期并发症的发生率,严重时可危及母儿生命安全。了解其发病机制、掌握不良妊娠结局,基于现有研究的生物标志物早期预测并识别CA,加强产前管理,将有助于降低母儿并发症的发生率。 Premature rupture of membranes(PROM)is a common complication during pregnancy,and one of the main risks associated with it is chorioamnionitis(CA).PROM combined with CA can cause fetal inflammatory response syndrome,increase the incidence of neonatal infectious diseases and perinatal complications,and in severe cases,it can endanger the lives of both the mother and the child.Understanding its pathogenesis,grasping adverse pregnancy outcomes,early prediction and identification of CA based on biomarkers from existing research,and strengthening prenatal management will help reduce the incidence of maternal and neonatal complications.
作者 侯璐 傅丹 HOU Lu;FU Dan(Yangzhou University,Yangzhou 225009,China;不详)
出处 《中外医学研究》 2025年第26期176-180,共5页 CHINESE AND FOREIGN MEDICAL RESEARCH
关键词 胎膜早破 绒毛膜羊膜炎 羊膜腔感染 不良妊娠结局 管理 新生儿 Premature rupture of membranes Chorioamnionitis Intraamniotic infection Adverse pregnancy outcome Management Newborn
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