摘要
目的调查卵巢癌患者延迟诊断情况,分析卵巢癌延迟诊断的影响因素。方法选择2021年1月—2023年9月就诊的卵巢癌患者纳入研究,以首次症状出现至确诊≥3个月判定为延迟诊断。收集延迟诊断者和未延迟诊断者的基本信息与社会因素(包括年龄、居住地、受教育水平、家庭收入、职业、BMI、婚姻状况、月经情况、医疗支付方式)、肿瘤相关因素[包括肿瘤家族史、组织学类型、国际妇产联盟(FIGO)分期、肿瘤位置、肿瘤大小、首发症状类型]和疾病认知情况(包括卵巢癌症状意识评分、卵巢癌担忧量表评分、健康信念情况和就医行为)。分别采用单因素分析和Logistic回归分析卵巢癌延迟诊断的影响因素。结果403例卵巢癌患者中,延迟诊断者106例、未延迟诊断者297例。延迟诊断者和未延迟诊断者年龄、居住地、受教育水平、家庭收入、肿瘤家族史、肿瘤组织学类型、FIGO分期、肿瘤位置差异有统计学意义(P均<0.05)。Logistic回归分析显示,患者的受教育水平(OR=0.606,95%CI:0.440~0.833,P=0.002)、肿瘤家族史(OR=0.462,95%CI:0.214~0.997,P=0.049)、情绪障碍(OR=1.332,95%CI:1.081~1.642,P=0.007)、实际障碍(OR=2.964,95%CI:2.195~4.004,P<0.001)是卵巢癌延迟诊断的独立影响因素。结论患者受教育水平、肿瘤家族史、情绪障碍、实际障碍是卵巢癌延迟诊断的独立影响因素。
Objective To investigate the status of delayed diagnosis in ovarian cancer(OC)patients and to analyze the key factors affecting the delayed diagnosis of this disease.Methods OC patients who received treatment at the study hospital from January 2021 to September 2023 were included.Patients were classified as having delayed diagnosis if the interval from the first appearance of symptoms to confirmed diagnosis was≥3 months,and thus they were divided into the delayed diagnosis group and non-delayed diagnosis group.Data were collected from both groups,including basic information and social factors(age,place of residence,education level,family income,occupation,BMI,marital status,menstrual status,medical payment method),tumor-related factors[family history of tumor,histological type,International Federation of Gynecology and Obstetrics(FIGO)stage,tumor location,tumor size,and type of initial symptom],and disease cognition(ovarian cancer symptom awareness score,ovarian cancer worry scale score,health belief,and health-seeking behavior).Univariate analysis and Logistic regression analysis were applied to screen for independent influencing factors of delayed diagnosis.Results A total of 403 OC patients were included,among whom 297 were in the non-delayed diagnosis group and 106 in the delayed diagnosis group.There were statistically significant differences between the two groups in age,place of residence,education level,family income,family history of tumor,tumor histological type,FIGO stage,and tumor location(all P<0.05).Logistic regression analysis showed that the education level[odd ratio(OR)=0.606;95%CI:0.440-0.833;P=0.002],family history of tumor(OR=0.462;95%CI:0.214-0.997;P=0.049),emotional barriers(OR=1.332;95%CI:1.081-1.642;P=0.007),and practical barriers(OR=2.964;95%CI:2.195-4.004;P<0.001)were independent risk factors for delayed diagnosis of OC.Conclusion Education level,family history of tumor,emotional barriers,and practical barriers are independent influencing factors of delayed diagnosis in OC patients.
作者
刘思宇
洪开
刘炎
蒲晓丽
冷小飞
黄润强
张春莲
LIU Siyu;HONG Kai;LIU Yan;PU Xiaoli;LENG Xiaofei;HUANG Runqiang;ZHANG Chunlian(Graduate School,Hubei University of Medicine,Shiyan 442000,China)
出处
《山东医药》
2025年第9期93-99,共7页
Shandong Medical Journal
关键词
卵巢癌
延迟诊断
疾病意识
情绪障碍
ovarian carcinoma
delayed diagnosis
disease awareness
emotional disorder
