摘要
目的比较两种清肠剂(硫酸镁钠钾口服用浓溶液和复方聚乙二醇电解质散)在肠道准备中的效果及不良反应。方法选取2024年1-11月在南京市中心医院消化内科需接受结肠镜检查的309例患者为研究对象,采用抽签法随机将其分为试验组(n=177,采用硫酸镁钠钾口服用浓溶液清肠)和对照组(n=132,采用复方聚乙二醇电解质散清肠)。对比两组患者口服清肠剂后的肠道清洁度、盲肠插管率、腺瘤检出率及不良反应发生情况。结果试验组左半结肠、横结肠、右半结肠的波士顿评分均高于对照组(P<0.05)。两组腺瘤检出率比较,差异无统计学意义(P>0.05);试验组盲肠插管率高于对照组(P<0.05)。口服清肠剂后,试验组不良反应发生率明显低于对照组(P<0.05)。结论硫酸镁钠钾口服用浓溶液和复方聚乙二醇电解质散作为清肠剂均能达到一定的清肠效果,但前者的清肠效果更优,盲肠插管率更高,不良反应发生率更低。
Objective To compare the efficacy and adverse reactions of two bowel cleansers,magnesium sulfate,sodium sulfate and potassium sulfate concentrate oral solution and compound polyethylene glycol electrolyte powder,in bowel preparation.Methods A total of 309 patients requiring electronic colonoscopy in the Department of Gastroenterology,Nanjing Central Hospital from January 2024 to November 2024 were randomized by lottery method into an experimental group(n=177,receiving magnesium sulfate,sodium sulfate and potassium sulfate concentrate oral solution for bowel preparation)and a control group(n=132,receiving compound polyethylene glycol electrolyte powder for bowel preparation).The bowel preparation quality,examination results(cecal intubation rate,adenoma detection rate),and incidence of adverse reactions of patients after oral laxative administration were compared between the two groups.Results The Boston Bowel Preparation Scale(BBPS)scores of the left colon,transverse colon,and right colon in the experimental group were higher than those in the control group(P<0.05).There was no significant difference in the adenoma detection rate between the two groups(P>0.05).The cecal intubation rate in the experimental group was higher than that in the control group(P<0.05).The incidence of adverse reactions after oral laxative administration in the experimental group was lower than that in the control group(P<0.05).Conclusion Both magnesium sulfate,sodium sulfate and potassium sulfate concentrate oral solution and compound polyethylene glycol electrolyte powder as bowel cleansers can achieve certain bowel cleansing effect.However,the former shows better bowel cleansing effect,higher cecal intubation rate,and lower incidence of adverse reactions.
作者
王钟晗
梁晓华
Wang Zhonghan;Liang Xiaohua(Department of Gastroenterology,Nanjing Central Hospital,Nanjing 210008,China)
出处
《成都医学院学报》
2025年第5期850-852,900,共4页
Journal of Chengdu Medical College
基金
南京市卫生和计划生育委员会医学科技发展项目(No:YKK22199)。
关键词
清肠剂
清肠效果
硫酸镁钠钾口服用浓溶液
复方聚乙二醇电解质散
不良反应
Bowel cleanser
Bowel cleansing effect
Magnesium sulfate,sodium sulfate and potassium sulfate concentrate oral solution
Compound polyethylene glycol electrolyte powder
Adverse reaction
