摘要
该文基于肠道菌群的作用机制,探讨了中医治疗功能性便秘(Functional constipation,FC)与肠道菌群的联系,结合中医治疗FC辨证论治经验,从肠道菌群变化情况分析出对中医治疗FC的指导意义。认为中医辨证论治对患者的肠道菌群起到了明显的调节作用,其中益生菌厚壁菌门(乳杆菌)、拟杆菌门(普雷沃氏菌科、乳酸杆菌属)以及放线菌门(双歧杆菌)的增多最有意义,除此之外,在治疗气虚便秘等实验中发现,厚壁菌门与拟杆菌门的比值下调对肠道功能恢复意义显著。
Based on the mechanism of action of the intestinal microbiota,this article explores the connection between traditional Chinese medicine(TCM)treatment of functional constipation(FC)and the intestinal microbiota.By combining the experience of TCM in the diagnosis and treatment of FC,it analyzes the guiding significance for TCM treatment of FC from the perspective of changes in the intestinal microbiota.It is believed that TCM diagnosis and treatment have a significant regulatory effect on the intestinal microbiota of patients.Among them,the increase of beneficial bacteria such as the Firmicutes(Lactobacillus),Bacteroidetes(Prevotellaceae,Lactobacillus),and Actinobacteria(Bifidobacterium)is of the greatest significance.In addition,in experiments treating qi-deficiency constipation and others,it was found that the down-regulation of the ratio of Firmicutes to Bacteroidetes is significantly meaningful for the recovery of intestinal function.
作者
吴研
周天羽
WU Yan;ZHOU Tianyu(Liaoning University of Chinese Medicine,Shenyang 110847,Liaoning,China;Affiliated Hospital of Liaoning University of Chinese Medicine,Shenyang 110032,Liaoning,China)
出处
《实用中医内科杂志》
2025年第8期51-55,共5页
Journal of Practical Traditional Chinese Internal Medicine
基金
全国名老中医药专家传承工作室建设项目(国中医药人教函[2022]75号)。
关键词
功能性便秘
肠道菌群
中医药
辨证论治
Functional constipation
Gut microbiota
Traditional Chinese medicine
Syndrome differentiation and treatment
