摘要
目的探究乌灵胶囊联合酒石酸唑吡坦片治疗失眠患者的疗效,对比分析联合用药方案与单一镇静催眠类药物干预在临床上的获益。方法收集2024年12月至2025年3月就诊于中国人民解放军联勤保障部队第九〇〇医院门诊辨证为心肾不交失眠患者的临床资料,根据治疗方法的不同分为观察组和对照组,每组30例。观察组采用乌灵胶囊联合酒石酸唑吡坦片治疗,对照组单独采用酒石酸唑吡坦片治疗。比较两组患者治疗前后的睡眠质量测评指标[匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)]、失眠严重程度指数(insomnia severity index,ISI)及心理健康评估维度[焦虑自评量表(self rating anxiety scale,SAS)和抑郁自评量表(self rating depression scale,SDS)]、中医证候积分、疗效等。结果经2周的临床干预,观察组患者的PSQI、ISI、SAS、SDS评分及中医证候积分和治疗总有效率等均优于对照组(P<0.05)。结论与单独使用酒石酸唑吡坦片比较,乌灵胶囊联合酒石酸唑吡坦片治疗心肾不交失眠患者的疗效更好,PSQI评分更低,情绪改善更明显且失眠伴随症状减轻。
Objective To explore the efficacy of Wuling capsule and zolpidem tartrate tablets in the treatment of insomnia patients,and to compare and analyze the clinical benefits of the combined medication scheme and single sedative-hypnotic drugs intervention.Methods To collect the clinical data of insomnia patients with heart kidney disharmony in the 900th Hospital of Joint Logistic Support Force of the People’s Liberation Army of China outpatient department from December 2024 to March 2025 as research materials.According to the different treatment method,patients were divided into observation group and control group,with 30 cases in each group.Patients in observation group were treated with Wuling capsule combined with zolpidem tartrate tablets,and patients in control group were treated with zolpidem tartrate tablets alone.The observation indexes of sleep quality evaluation index[Pittsburgh sleep quality index(PSQI)],insomnia severity index(ISI)and mental health evaluation dimension[self rating anxiety scale(SAS)and self rating depression scale(SDS)],traditional Chinese medicine syndrome score and therapeutic efficacy of two groups before and after treatment were compared.Results After 2 weeks of clinical intervention,the PSQI,ISI,SAS,SDS scores,traditional Chinese medicine symptom scores,and therapeutic efficacy of observation group patients were all better than those of control group(P<0.05).Conclusion Compared with zolpidem tartrate tablets alone,Wuling capsule combined with zolpidem tartrate tablets has better curative effect in the treatment of insomnia patients with“heart kidney disharmony”,lower PSQI score and more obvious emotional improvement,alleviated symptoms accompanying insomnia.
作者
林坤山
戢婷
LIN Kunshan;JI Ting(Department of Psychiatry,the 900th Hospital of Joint Logistic Support Force of the People’s Liberation Army of China,Fuzhou 350025,Fujian,China)
出处
《中国现代医生》
2025年第27期53-56,共4页
China Modern Doctor
关键词
失眠
乌灵胶囊
酒石酸唑吡坦片
焦虑
抑郁
Insomnia
Wuling capsule
Zolpidem tartrate tablets
Anxiety
Depression
