盆底超声参数联合血清松弛素、雌二醇诊断女性压力性尿失禁的价值

Value of detection of pelvic floor ultrasound parameters combined with serum relaxin and estradiol in diagnosis of female stress urinary incontinence

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摘要目的探讨盆底超声参数联合血清松弛素(RLX)、雌二醇(E_(2))水平在女性压力性尿失禁(SUI)诊断中的价值。方法选取127例SUI产妇作为SUI组,另选取同期无SUI的127例产妇作为对照组,比较2组产妇的盆底超声参数[膀胱颈移动度(BND)、膀胱尿道后角(PUVA)、尿道旋转角(URA)]及血清RLX、E_(2)水平。采用二元Logistic回归分析筛选女性SUI的独立影响因素,并通过受试者工作特征(ROC)曲线分析各指标单独及联合应用对女性SUI的诊断效能。结果SUI组BND、PUVA、URA大于对照组,血清RLX水平高于对照组,血清E_(2)水平低于对照组,差异有统计学意义(P<0.05)。二元Logistic回归分析结果显示,BND、PUVA、E_(2)是女性SUI的独立影响因素(P<0.05)。ROC曲线分析显示,BND、PUVA、URA、RLX、E_(2)单独及联合诊断女性SUI的曲线下面积(AUC)分别为0.775、0.814、0.777、0.749、0.746及0.932,敏感度分别为90.6%、86.6%、57.5%、48.8%、100.0%及92.1%,特异度分别为53.5%、68.5%、91.3%、92.1%、49.6%及77.2%。结论盆底超声参数BND、PUVA、URA及血清RLX、E_(2)水平联合检测对女性SUI具有较高的诊断价值。 Objective To investigate the value of detection of pelvic floor ultrasound parameters combined with serum relaxin(RLX)and estradiol(E_(2))levels in diagnosis of female stress urinary incontinence(SUI).Methods A total of 127 puerperae with SUI were selected as SUI group,and another 127 puerperae without SUI during the same period were selected as control group.The pelvic floor ultrasound parameters[bladder neck descent(BND),postvoid residual angle of the bladder-urethra(PUVA),and urethral rotation angle(URA)]and serum RLX and E_(2)levels were compared between the two groups.Binary Logistic regression analysis was used to screen independent influencing factors of female SUI,and the diagnostic efficacy of each index alone and their combination for female SUI was analyzed through the receiver operating characteristic(ROC)curve.Results The BND,PUVA,and URA values in the SUI group were greater than those in the control group,the serum RLX level was higher,and the serum E_(2)level was lower,with statistically significant differences(P<0.05).Binary Logistic regression analysis showed that BND,PUVA,and E_(2)were independent influencing factors of female SUI(P<0.05).ROC curve analysis revealed that the areas under the curve(AUCs)for the diagnosis of female SUI by BND,PUVA,URA,RLX,and E_(2)alone and their combination were 0.775,0.814,0.777,0.749,0.746,and 0.932,respectively.Their sensitivities were 90.6%,86.6%,57.5%,48.8%,100.0%,and 92.1%,and the specificities were 53.5%,68.5%,91.3%,92.1%,49.6%,and 77.2%,respectively.Conclusion The combined detection of pelvic floor ultrasound parameters including BND,PUVA,URA,and serum RLX and E_(2)levels has a high diagnostic value for female SUI.

作者王颛婷张慧雅佘雯 WANG Zhuanting;ZHANG Huiya;SHE Wen(Department of Ultrasound,Xidian Group Hospital,Xi′an,Shaanxi,710077;Department of Obstetrics and Gynecology,Xidian Group Hospital,Xi′an,Shaanxi,710077;Department of Ultrasound,Xi′an International Medical Center Hospital,Xi′an,Shaanxi,710054)

机构地区西电集团医院超声科西电集团医院妇产科西安国际医学中心医院超声科

出处《实用临床医药杂志》 2025年第15期83-86,91,共5页 Journal of Clinical Medicine in Practice

基金陕西省卫生健康委科研项目(20203516)。

关键词压力性尿失禁盆底超声松弛素雌二醇产妇膀胱颈移动度膀胱尿道后角尿道旋转角 stress urinary incontinence pelvic floor ultrasound relaxin estradiol puerpera bladder neck descent postvoid residual angle of the bladder-urethra urethral rotation angle