摘要
目的 分析2023—2024年安徽省报告猴痘突发公共卫生事件及相关病例的流行病学及临床特征,为猴痘疫情防控工作提供参考。方法 通过“中国疾病预防控制信息系统”获取创建时间为2023—2024年、报告地区为安徽省的猴痘突发公共卫生事件信息及相关病例的个案信息。采用描述性流行病学方法分析事件基本情况及病例的三间分布、就诊情况和临床特征等。结果 2023年安徽省9个地市19个县(区)报告19起猴痘突发公共卫生事件,共涉及病例22例;2024年未报告。突发事件主要发生在6—8月(73.7%,14/19),合肥市占比最高(26.3%,5/19)。2起为聚集性疫情,共报告5例病例,感染来源可能为与省外人员通过男男性行为接触传播。突发事件涉及病例均为男男性行为者(men who have sex with men, MSM)人群,77.3%(17/22)病例自述既往感染HIV;潜伏期中位数为6 d;86.4%(19/22)病例为主动就诊发现;9例为首次就诊确诊,其中8例就诊医院为艾滋病抗病毒治疗定点医疗机构;就诊科室以皮肤科/感染科为主(63.2%,12/19);确诊前就诊次数与首次就诊科室和首次就诊医院是否为艾滋病抗病毒治疗定点医疗机构均存在相关性(P<0.05)。病例首发症状以皮疹(50.0%,11/22)和发热(22.7%,5/22)为主。结论 安徽省猴痘疫情处于低流行散发态势,病例首发症状以皮疹为主。鉴于猴痘在MSM人群中存在隐匿性传播风险,需加强重点人群宣教干预。
Objective To analyze the epidemiological and clinical characteristics of the reported mpox public health emergencies and related cases reported in Anhui Province from 2023 to 2024,providing a reference for mpox prevention and control.Methods Information on mpox public health emergencies and individual cases reported in Anhui Province from 2023 to 2024 was obtained through the China Information System for Disease Control and Prevention.Descriptive epidemiological methods were employed to analyze the basic situation of the events,as well as the temporal,spatial,and population distributions of reported cases,their healthcare-seeking behaviors,and clinical features.Results In 2023,19 mpox public health emergencies involving 22 cases were reported in 19 counties(districts)across 9 prefectures in Anhui Province,while no cases were reported in 2024.The reported events were concentrated between June and August(73.7%,14/19),with Hefei City accounting for the highest proportion(26.3%,5/19).Two of the events were clustered outbreaks,involving a total of 5 cases,the source of infection was possibly attributed to transmission through sexual contact with men who have sex with men(MSM)from other provinces.All involved cases were MSM,77.3%(17/22)of the cases self-reporting previous HIV infection;the median incubation period was 6 d,and 86.4%(19/22)were identified through self-initiated medical visits.Nine cases were confirmed on their first medical visit,eight of whom consulted hospitals designated for antiretroviral therapy of AIDS.The main departments for medical consultation are Dermatology and Infectious Diseases(63.2%,12/19).The number of visits prior to diagnosis was associated with both the department visited at the first consultation and whether the first visit was the designated hospital for antiretroviral therapy for AIDS(both P<0.05).Rash(50.0%,11/22)and fever(22.7%,5/22)were the initial symptoms.Conclusion Mpox in Anhui Province is at a low endemic level with sporadic cases,and rash is the primary initial symptom.Given the risk of hidden transmission of mpox among MSM,health education and targeted interventions for this key population should be strengthened.
作者
滕雪娇
程树林
蒋斌
邓舒
赵玉秋
操治国
TENG Xuejiao;CHENG Shulin;JIANG Bin;DENG Shu;ZHAO Yuqiu;CAO Zhiguo(Anhui Provincial Center for Disease Control and Prevention,Hefei,Anhui 230601,China;Laian County Center for Disease Control and Prevention,Laian,Anhui 239200,China)
出处
《中国热带医学》
北大核心
2025年第7期843-847,共5页
China Tropical Medicine
基金
安徽省疾病预防控制中心青年科研项目(No.JKQN20230210)。
关键词
猴痘
突发公共卫生事件
皮疹
发热
HIV
男男性行为者
流行病学特征
临床症状
Mpox
public health emergencies
rash
fever
HIV
men who have sex with men
epidemiological characteristics
clinical symptoms
