摘要
猪流行性腹泻(porcine epidemic diarrhea,PED)是由猪流行性腹泻病毒(porcine epidemic diarrhea virus,PEDV)感染引起的一种高度接触性肠道传染病,以急性水样腹泻、呕吐和新生仔猪高死亡率为特征。自2010年我国暴发PED以来,PEDV已发生多次变异,针对经典毒株的疫苗对变异毒株的交叉免疫保护效果不佳,且无特效药物对该病进行治疗。基于此,文章从PEDV基因组及流行病学特征入手,重点介绍PEDV实验室诊断方法的研究进展,以期为该病的临床诊断和防控提供一定参考。
porcine epidemic diarrhea(PED)is a highly contagious intestinal infectious disease caused by porcine epidemic diarrhea virus(PEDV)infection.It is characterized by acute watery diarrhea,vomiting and a high mortality rate among newborn piglets.Since the outbreak of PED in China in 2010,PEDV has undergone multiple mutations.The cross-immune protection effect of vaccines against classic strains against variant strains is poor,and there are no specific drugs to treat this disease.Based on this,starting from the genomic and epidemiological characteristics of PEDV,this article focuses on introducing the research progress of laboratory diagnostic methods for PEDV,with the aim of provide a reference for the clinical diagnosis and prevention and control of this disease.
作者
丁林玲
陈云蕾
杨宗照
刘璐
邵婷婷
徐廷帅
张帅
Ding Linling;Chen Yunlei;Yang Zongzhao;Liu Lu;Shao Tingting;Xu Tingshuai;Zhang Shuai(Management Center of Equine Disease Free Zone of Tonglu,Zhejiang Hangzhou 310000;Hangzhou Agricultural Law Enforcement Supervision and Guidance Center,Zhejiang Hangzhou 310000;Department of Animal Science,Ganzhou Polytechnic College,Jiangxi Ganzhou 341000;Key Laboratory of Animal Pathogens and Biosafety Prevention and Control in Ganzhou,Jiangxi Ganzhou 341000)
出处
《现代畜牧兽医》
2025年第8期92-96,共5页
Modern Journal of Animal Husbandry and Veterinary Medicine
基金
杭州市桐庐县511中青年人才培养工程
赣州职业技术学院科研项目(X-2024-KXJS-03)。
