摘要
为提高医用敷料对伤口渗液的传导性,将具有优良吸湿、导湿性的莲纤维分散在聚乙烯吡咯烷酮(PVP)中,采用静电纺丝技术制备了莲纤维/PVP纳米医用敷料。采用SEM对莲纤维/PVP纳米医用敷料的微观形貌、直径分布和孔隙率进行了表征和统计,通过水接触角、吸液率、水蒸气透过率测定以及力学性能和抑菌性能测试,考察了莲纤维添加量(以PVP质量为基准,下同)对其结构和性能的影响。结果表明,莲纤维/PVP纳米医用敷料的纤维分布均匀,表面无串珠,呈互连的多孔结构。在PVP质量浓度为100 g/L、莲纤维添加量为5.5%的条件下,制备的莲纤维/PVP纳米医用敷料(L-5.5/PVP-100)水接触角为32.6°、吸液率为487.02%,具有超润湿性;L-5.5/PVP-100的抗拉强度为3.66 MPa、断裂伸长率为18.53%,并对金黄色葡萄球菌有一定的抑制作用;由莲纤维添加量1.5%制备的莲纤维/PVP纳米医用敷料(L-1.5/PVP-100)的纤维平均直径(318.57 nm)最小,具有最高的孔隙率(72.39%)和水蒸气透过率〔2396.38 g/(m^(2)·24 h)〕,呈超导湿性,有利于水蒸气的传输。
In order to improve the conductivity of medical dressing to wound transudate,lotus fiber/polyvinylpyrrolidone(PVP)nano-medical dressing was prepared by dispersing lotus fiber,with excellent hygroscopicity and water transport performance,into PVP via electrospinning technology,characterized and statistically analyzed by SEM for microscopic morphology,diameter distribution and porosity.The effects of addition amount of lotus fiber(based on the mass of PVP,the same below)on its structure and properties were investigated through measurement on water contact angle,liquid absorption rate,water vapor transmission rate,mechanical properties and antibacterial properties.The results showed that the prepared lotus fiber/PVP nano-medical dressing exhibited uniform fiber distribution,an interconnected porous structure with no beads appearing on the surface.when the mass concentration of PVP was 100 g/L,and the addition amount of lotus fibers was 5.5%,the prepared lotus fiber/PVP nano-medical dressing(L-5.5/PVP-100)displayed a water contact angle of 32.6°and liquid absorption rate of 487.02%,indicating ultra-wettability.In addition,L-5.5/PVP-100 showed a tensile strength of 3.66 MPa,an elongation at break of 18.53%,and certain inhibitory effect on Staphylococcus aureus.The lotus fiber/PVP nano-medical dressing(L-1.5/PVP-100)prepared with addition amount of 1.5%lotus fiber had the smallest average fiber diameter(318.57 nm)and the highest porosity(72.39%)as well as water vapor transmission rate[2396.38 g/(m^(2)·24 h)],and showed superconducting moisture,which was conducive to the transport of water vapor.
作者
杨瑞瑞
郭嫣
陈莉
刘铭燊
YANG Ruirui;GUO Yan;CHEN Li;LIU Mingshen(School of Textile Science and Engineering,Xi'an Polytechnic University,Xi'an 710048,Shaanxi,China;Jiangsu Deweilan Medical Equipment Co.,Ltd.,Taizhou 225300,Jiangsu,China)
出处
《精细化工》
北大核心
2025年第9期1968-1975,1985,共9页
Fine Chemicals
基金
中国纺织工业联合会科技指导性项目(2017012)。
关键词
莲纤维
润湿性
导湿性
医用敷料
静电纺丝
功能材料
lotus fiber
wetting property
water transport performance
medical dressings
electrospinning
functional materials
