摘要
目的:针对中国癌症患者失志综合征检出率进行系统回顾和Meta分析,为制定公共卫生战略提供循证依据。方法:系统检索Web of Science、Cochrane Library、PubMed、EMbase、Scopus、中国知网、中国生物医学文献服务系统、万方数据库、维普数据库,检索时限自建库至2024年3月12日,采用Stata 17.0软件进行Meta分析,敏感度分析、亚组分析寻找异质性来源,采用漏斗图、egger′s检验识别发表偏倚。结果:共纳入24篇包括6580例研究对象。Meta分析结果显示,我国癌症患者失志综合征检出率为61.9%(95%CI=0.525~0.708),亚组分析结果显示,东部、中西部、台湾地区癌症患者失志综合征检出率分别为47.2%、82.4%、41.6%。妇科癌症、其他消化道癌症、肺癌、肝癌失志综合征检出率分别为67.9%、60.1%、86.6%、99.9%(均P<0.05)。结论:在我国癌症患者失志综合征检出率普遍较高,在某种疾病及部分地区表现更为突出,肺癌、肝癌以及中西部地区癌症患者失志综合征检出率更高。临床医务人员应注意早期识别,并进行针对性地干预,以避免患者进一步的身体或心理的伤害,进而提高患者整体生活质量。
Objective To conduct a systematic review and meta-analysis of the prevalence of demoralization syndrome in cancer patients in China,and provide evidence-based data for the formulation of public health strategies.Methods A sys-tematic search was conducted across multiple databases,including Web of Science,Cochrane Library,PubMed,EMbase,Scopus,CNKI,China Biomedical Literature Service System(CBM),Wanfang Data,and VIP from the inception of the da-tabases to March 12,2024.Meta-analysis,sensitivity analysis,and subgroup analysis were performed using Stata 17.0 to identify sources of heterogeneity.Funnel plots and Egger's test were used to detect publication bias.Results A total of 24 studies with 6,580 subjects were included.The meta-analysis indicated that the prevalence of demoralization syndrome a-mong cancer patients in China was 61.9%(95%CI=0.525~0.708).Subgroup analysis revealed that the prevalence rates of demoralization syndrome were 47.2%,82.4%,and 41.6%for patients in Eastern,Central and Western China,and Tai-wan,respectively.Those for gynecological cancer,other gastrointestinal cancers,liver cancer,and lung cancer were 679%,60.1%,86.6%,and 99.9%,respectively(all P<0.05).Conclusion The prevalence of demoralization syndrome is notably high among cancer patients in China,with particularly elevated rates observed in specific diseases,such as lung cancer and liver cancer,as well as in the central and western regions.Clinical staff should focus on early identification and implement targeted interventions to prevent further physical or psychological harm to patients,thereby improving their over-all quality of life.
作者
谢小蔓
杨继维
沈俊明
高淑平
付钰澳
朱树贞
姜华
XIE Xiao-man;YANG Ji-wei;SHEN Jun-ming;GAO Shu-ping;FU Yu-ao;ZHU Shu-zhen(School of Nursing,Hubei University of Medicine,Shiyan,Hubei 442000;Department of Traditional Chinese Medicine,Beijing Puren Hospital,Beijing 100010;Department of Rehabilitation,Suizhou Hospital,Hubei University of Medicine,Suizhou,Hubei 441300;Department of Nursing,Xiangyang First People's Hospital,Hubei University of Medicine,Xiangyang,Hubei 441000,China)
出处
《湖北医药学院学报》
2025年第4期467-473,共7页
Journal of Hubei University of Medicine
基金
中华医学会杂志社护理学科研究课题(CMAPH NRG2021031)
湖北医药学院研究生科技创新项目(YC2024066)。
