摘要
长久以来,骨质疏松症与心血管疾病被视为互相独立存在,但流行病学研究揭示了它们之间存在许多确凿的关联证据。因此,患有骨质疏松症骨折病史或骨密度较低的患者,患冠状动脉疾病的风险通常高于非骨质疏松患者。另一方面,心血管疾病患者发生骨质流失和骨质疏松性骨折的风险也较高。与心血管疾病之间的关联,有部分原因是因为二者有共同的危险因素,如绝经后女性雌激素缺乏、吸烟、体育锻炼不足等。随着这些研究的不断进展,二者之间的相关性也被越来越明确,这对于药物的研发、降低二者并存患者的死亡率等有着重大意义。所以该文研究使用CT值进行骨质疏松症的机会性筛查,避开传统骨密度测量方式,扩大骨质疏松的筛查,旨在探讨椎体松质骨CT值与动脉粥样硬化性心血管疾病之间的关系,为根据早期骨质疏松检测结果筛选冠心病高风险人群提供科学依据。
For a long time,Osteoporosis and cardiovascular diseases have been considered independent conditions;however,epidemiological studies have revealed substantial evidence of their interconnections.Therefore,patients with a history of osteoporotic fractures or low bone density are generally at a higher risk of coronary artery disease compared to those without osteoporosis.On the other hand,patients with cardiovascular diseases are also at an increased risk of bone loss and osteoporotic fractures.The association between osteoporosis and cardiovascular diseases is partly attributed to shared risk factors,such as estrogen deficiency in postmenopausal women,smoking,and insufficient physical activity.As research on this topic progresses,the correlation between these two conditions has become increasingly evident,which holds significant implications for drug development and reducing the mortality rate among patients with both conditions.This study uses CT values for opportunistic osteoporosis screening,bypassing traditional bone density measurement methods,to expand osteoporosis screening.The aim is to explore the relationship between vertebral trabecular bone CT values and atherosclerotic cardiovascular diseases,providing scientific evidence for selecting high-risk coronary artery disease populations based on early osteoporosis detection results.
作者
葛子路
刘少强
GE Zilu;LIU Shaoqiang(The First Clinical Medical School of Gannan Medical University,Ganzhou,Jiangxi 341000,China;Department of Medical Imaging,The First Affiliated Hospital of Gannan Medical University,Ganzhou,Jiangxi 341000,China)
出处
《现代医药卫生》
2025年第8期1950-1953,1958,共5页
Journal of Modern Medicine & Health
关键词
心血管疾病
骨质疏松
椎体松质骨CT值
冠心病
心力衰竭
综述
Cardiovascular disease
Osteoporosis
CT value of vertebral cancellous bone
Coronary artery disease
Heart failure
Review
