摘要
将载银活性炭纤维作为过滤材料,研究其用于L-羟脯氨酸的精制条件。采用前驱体载银法制备出载银活性炭纤维,经检验银粒子结合牢固,不易脱落。研究了载银活性炭纤维去除L-羟脯氨酸中需氧菌、霉菌和酵母菌以及内毒素的条件。结果显示,使用3层载银活性炭纤维作为过滤材料,重复使用9次,L-羟脯氨酸产品中需氧菌菌落数为25 CFU/g,去除率为68.2%;霉菌和酵母菌菌落数为15 CFU/g,去除率为76.7%。使用单层载银活性炭纤维作为过滤材料,重复使用10次,内毒素含量为25.4 EU/g,去除率可达80.9%。产品理化指标符合标准,产品中未检出银和银离子。结果表明,采用3层载银活性炭纤维,重复使用9次,能同时满足除去需氧菌、霉菌和酵母菌以及内毒素的要求。
The silver loaded activated carbon fiber was used as a filtering material,and its refining conditions for L-hydroxyproline were studied.The silver-loaded activated carbon fibers were prepared by precursor silver loading method,and the silver particles were firmly bound and not easily detached.The conditions for removing aerobic bacteria,fungi,yeast and endotoxins from L-hydroxyproline using silver loaded activated carbon fibers were studied.The results showed that when 3-layer of silver loaded activated carbon fibers were used as filter materials and reused for 9 times,the aerobic bacterial colony count in L-hydroxyproline products was 25 CFU/g,with a removal rate of 68.2%.The colony count of fungi and yeasts were 15 CFU/g,with a removal rate of 76.7%.Using single-layer silver loaded activated carbon fiber as the filtering material and reusing for 9 times,the endotoxin content was 25.4 EU/g and the removal rate could reach 80.9%.The physical and chemical indicators of the product could meet the standards,and no silver or silver ions were detected in the product.The results showed that using 3-layer silver loaded activated carbon fibers and reusing for 9 times can simultaneously meet the requirements for removing aerobes,fungi,yeasts and endotoxins.
作者
刘兴宇
浦军平
沈霞
张峰
张春枝
LIU Xingyu;PU Junping;SHEN Xia;ZHANG Feng;ZHANG Chunzhi(School of Biological Engineering,Dalian Polytechnic University,Dalian 116034,China;Zhangjiagang Huachang Pharmaceutical Company Limited,Suzhou 215600,China;School of Textile,Clothing and Materials,Shazhou Professional Institute of Technology,Suzhou 215600,China)
出处
《大连工业大学学报》
2025年第4期271-275,共5页
Journal of Dalian Polytechnic University
基金
张家港市校企合作产学研前瞻性项目(ZKYY2220).
关键词
载银活性炭纤维
L-羟脯氨酸
内毒素
silver-loaded activated carbon fiber
L-hydroxyproline
endotoxin
