摘要
基孔肯雅热是基孔肯雅病毒(CHIKF)感染引起的传染病。CHIKF主要经伊蚊叮咬传播。CHIKF引发的急性病症以发热、皮疹和严重关节痛为主要特征。现已有两种疫苗(IXCHIQ、VIMKUNYA)获批可用于重点人群预防基孔肯雅热,但尚未广泛使用。目前尚无针对CHIKF的特异性抗病毒药物获批上市,临床上以对症支持治疗为主。本文在综述CHIKF的流行病学、传播风险及防控策略的基础上,重点阐述CHIKF疫苗使用和治疗管理的最新进展。
Chikungunya fever(CHIKF)is an infectious disease caused by Chikungunya virus(CHIKV)infection.The CHIKV is mainly transmitted through the bites of Aedes mosquitoes.The acute symptoms caused by the CHIKV are mainly characterized by fever,rash and severe joint pain.Two vaccines(IXCHIQ and VIMKUNYA)have now been approved for the prevention of CHIKF in key populations,but they have not yet been widely used.At present,there are no specific antiviral drugs approved for marketing against the CHIKV,and clinical treatment mainly focuses on symptomatic supportive therapy.Based on a review of the epidemiology,transmission risks,and prevention and control strategies of the CHIKV,this article focuses on describing the latest progress in the use of Chikungunya vaccines and treatment management.
作者
龚祖康
徐斌
林文珍
GONG Zukang;XU Bin;LIN Wenzhen(Nanning Fifth People’s Hospital,Nanning 530001,China;The Affiliated Mental Health Center of Guangxi Medical University,Nanning 530001,China;Nanning Center for Disease Control and Prevention,Nanning 530023,China;Department of Biochemistry and Molecular Biology,Guangxi Medical University,Nanning 530021,China;Key Laboratory of Biological Molecular Medicine Research,Guangxi Medical University,Education Department of Guangxi Zhuang Autonomous Region,Nanning 530021,China)
出处
《广西医科大学学报》
2025年第4期483-488,共6页
Journal of Guangxi Medical University
基金
广西疾病预防控制研究课题资助项目(No.GXJKKJ24Z002)。
关键词
基孔肯雅热
防控
治疗
Chikungunya fever
prevention
treatment
