摘要
目的探讨血府逐瘀汤加减治疗对心血瘀阻型冠心病稳定型心绞痛患者心绞痛发作情况及血液流变学指标的影响。方法选择2023年7月—2024年10月略阳县中医医院收治的100例心血瘀阻型冠心病稳定型心绞痛患者为研究对象,按随机数字表法将其分为对照组和观察组,各50例。对照组采用西医常规治疗,观察组在对照组基础上联合血府逐瘀汤加减治疗。对比两组的临床疗效、中医证候积分、心绞痛发作情况、血液流变学指标、不良反应发生情况。结果观察组治疗总有效率为96.00%,高于对照组的82.00%,差异有统计学意义(P<0.05)。治疗后,观察组胸部刺痛、心悸、胸闷评分均低于对照组,组间差异有统计学意义(P<0.05);观察组心绞痛发作频率慢于对照组,每次发作持续时间短于对照组,组间差异有统计学意义(P<0.05);观察组全血高切黏度、红细胞变形指数、血浆黏度、纤维蛋白原水平均低于对照组,组间差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论心血瘀阻型冠心病稳定型心绞痛患者应用血府逐瘀汤加减治疗可减轻临床症状,改善血液流变学指标,且安全性高。
Objective Exploring the effect of modified Xuefu Zhuyu Decoction treatment on angina attacks situation and hemorheological indicators in patients with stable angina pectoris of coronary heart disease with heart blood stasis obstruction type.Methods Selecting 100 patients with stable angina pectoris of coronary heart disease with heart blood stasis obstruction type admitted to Lueyang County Traditional Chinese Medicine Hospital from July 2023 to October 2024 as the research subjects,according to the random number table method,they were divided into a control group and an observation group,with 50 cases in each group.The control group was treated with conventional Western medicine,while the observation group was treated with modified Xuefu Zhuyu Decoction on the basis of the control group.Compare the clinical efficacy,traditional Chinese medicine syndrome score,angina attacks situation,hemorheological indicators,and occurrence of adverse reactions between the two groups.Results The total effective rate of the observation group was 96.00%,which was higher than the 82.00%of the control group,the difference was statistically significant(P<0.05).After treatment,the chest pain,palpitations,and chest tightness scores in the observation group were lower than those in the control group,the differences between the groups were statistically significant(P<0.05);the frequency of angina attacks in the observation group was slower than that in the control group,and the duration of each attack was shorter than that in the control group,the differences between the groups were statistically significant(P<0.05);the whole blood high shear viscosity,erythrocyte deformability index,plasma viscosity,and fibrinogen levels in the observation group were lower than those in the control group,the differences between the groups were statistically significant(P<0.05).Comparison of the incidence of adverse reactions between two groups,the difference was not statistically significant(P>0.05).Conclusion The modified Xuefu Zhuyu Decoction treatment can alleviate clinical symptoms in patients with stable angina pectoris of coronary heart disease with heart blood stasis obstruction type,improve hemorheological indicators,and has high safety.
作者
梁略军
LIANG Lvejun(Department of Preventive Treatment of Diseases in Traditional Chinese Medicine,Lueyang County Traditional Chinese Medicine Hospital,Lueyang 724300,China)
出处
《反射疗法与康复医学》
2025年第9期66-70,共5页
Reflexology And Rehabilitation Medicine
关键词
冠心病
稳定型心绞痛
心血瘀阻型
血府逐瘀汤加减
中医证候积分
心绞痛发作情况
血液流变学指标
Coronary heart disease
Stable angina pectori
Heart blood stasis obstruction type
Modified Xuefu Zhuyu Decoction
Traditional Chinese medicine syndrome score
Angina attacks situation
Hemorheological indicators
