摘要
目的:研究静息心率(RHR)对慢性心力衰竭(CHF)患者心功能指标及预后的影响。方法:选择2022年1月至2023年9月南京市江宁中医院心内科门诊和住院诊治的CHF患者103例。根据RHR分为低心率组(RHR<80次/min)62例、高心率组(RHR≥80次/min)41例。比较两组一般资料、纽约心脏病协会(NYHA)心功能分级、B型利钠肽(BNP)水平、左室射血分数(LVEF)、6min步行距离(6MWD)、6min步行试验(6MWT)前、后血压及运动后心率;随访6个月,比较两组患者3个月、6个月因心力衰竭加重再入院率。结果:与低心率组比较,高心率组6MWT后心率[109(100.0,119.0)次/min比91.5(84.0,105.2)次/min]、BNP水平[100(39.5,210.0)pg/ml比55.75(29.5,106.9)pg/ml]均显著升高(P<0.05或<0.01)。Spearman相关性分析表明,CHF患者RHR与BNP、6MWT后心率呈显著正相关(r=0.229、0.541,P=0.020、<0.001),与6MWD呈显著负相关(r=-0.221,P=0.025);高心率组3个月、6个月因心力衰竭加重再入院率分别为26.83%、51.22%,显著高于低心率组的9.68%、16.13%,(P=0.022、<0.001)。结论:CHF患者RHR与BNP、6MWD及6MWT后心率密切相关。高心率患者因心力衰竭加重再入院风险增加。
Objective:To investigate the effects of resting heart rate(RHR)on cardiac function indexes and prognosis in patients with chronic heart failure(CHF).Methods:A total of 103 CHF patients who were treated in the outpatient and inpatient departments in the Cardiology Department of Nanjing Jiangning Hospital of Traditional Chinese Medicine between January 2022 and September 2023 were selected.According to RHR,patients were divided into low heart rate(HR)group(RHR<80 beats/min,n=62)and high HR group(RHR≥80 beats/min,n=41).General data,New York Heart Association(NYHA)cardiac function class,B-type natriuretic peptide(BNP)level,left ventricular ejection fraction(LVEF),6min walking distance(6MWD),blood pressure before and after 6 min walking test(6MWT)and HR after 6MWT were compared between the two groups.After 6-month follow-up,heart failure aggravation-caused readmission rates at 3 months and 6 months were compared between the two groups.Results:Compared to patients in the low HR group,those in the high HR group had significant higher HR after 6MWT[109(100.0,119.0)beats/min vs.91.5(84.0,105.2)beats/min]and BNP level[100(39.5,210.0)pg/ml vs.55.75(29.5,106.9)pg/ml](P<0.05 or<0.01).Spearman correlation analysis showed that RHR was significantly positively correlated with BNP level and HR after 6MWT(r=0.229,0.541,P=0.020,<0.001),and significantly negatively correlated with 6MWD(r=-0.221,P=0.025)in CHF patients.Heart failure aggravation-caused readmission rate at 3 months and 6 months in high HR group was 26.83%and 51.22%respectively,which were significantly higher than those(9.68%,16.13%)of the low HR group(P=0.022,<0.001).Conclusion:In CHF patients,RHR was closely associated with BNP,6MWD and HR after 6MWT.Heart failure aggravation-caused readmission rate significantly increased in high HR group.
作者
夏敏
韦锋
XIA Min;WEI Feng(Department of Cardiology,Nanjing Jiangning Hospital of Traditional Chinese Medicine,Nanjing,Jiangsu,211100,China)
出处
《心血管康复医学杂志》
2025年第4期441-445,共5页
Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词
心力衰竭
心率
利钠肽
脑
Heart failure
Heart rate
Natriuretic peptide,brain
