摘要
目的:本共识为常压饱和吸氧的临床应用提供理论及技术指导。方法:系统阐述了饱和吸氧的必要性、设计原理、生理机制、临床应用规范及安全操作指南等,比较了采用不同吸氧方法时组织氧分压变化,旨在为临床氧疗提供循证学依据。结果:饱和吸氧较鼻导管吸氧能大幅提升组织氧分压,较经鼻高流量吸氧在提升组织氧分压的同时能大幅减少耗氧量,规避了高压氧治疗潜在风险与适应证和禁忌证的限制,可用于猝死、中毒、休克等急性缺氧性脑病的抢救治疗,颅脑及脊髓损伤、脑卒中、脑炎、皮肤溃疡等慢性缺氧性疾病的康复治疗,但不适用于慢阻肺及严重二氧化碳潴留的疾病,制定了应用原则及操作规范。结论:常压饱和吸氧为临床提供了一条新的氧疗途径。
Objective:This consensus provides technical guidance for the clinical application of normobaric saturated oxygen therapy(NSOT).Methods:The necessity,design principles,physiological mechanisms,clinical application standards,and safety operation guidelines of saturated oxygen therapy were systematically explained.The changes in tissue oxygen partial pressure were measured under different oxygen therapy methods,providing evidence-based support for clinical oxygen therapy.Results:Based on current literature and experimental data,saturated oxygen therapy significantly enhances tissue oxygen partial pressure compared to nasal cannula oxygen delivery.When compared to high-flow nasal cannula(HFNC)therapy,saturated oxygen therapy achieves superior tissue oxygenation while substantially reducing oxygen consumption.This approach circumvents the inherent risks and contraindications of hyperbaric oxygen therapy(HBOT).It is clinically applicable for emergency management of acute hypoxic encephalopathies(e.g.,sudden cardiac arrest,poisoning,shock)and rehabilitation of chronic hypoxic disorders(e.g.,traumatic brain/spinal cord injuries,stroke,encephalitis,cutaneous ulcers).Conclusion:NSOT provides a new pathway for oxygen therapy in clinical practice.
作者
丁建章
陈新平
高甜
潘树义
李航
暴军香
李佐民
秦慧
李丹
Ding Jianzhang;Chen Xinping;Gao Tian;Pan Shuyi;Li Hang;Bao Junxiang;Li Zuomin;Qin Hui;Li Dan(Beijing Haidian hospital,Beijng 100000,China;the Sixth Medical Center of PLA General Hospital,Beijing 100000,China;Air Force Medical University,Xi’an 710000,China;Chenzhou No.1 People′s Hospital,Chenzhou 450000,China;The First People's Hospital of Nanning,Nanning 210000,China;West China Hospital of Sichuan University,Chendu 610000,China)
出处
《中国康复》
2025年第8期451-457,共7页
Chinese Journal of Rehabilitation
关键词
常压饱和吸氧
氧分压
专家共识
normobaric saturated oxygen therapy
oxygen partial pressure
expert consensus
