摘要
目的 比较使用压缩感知(CS)加速技术的5.0T梯度回波序列冠状动脉磁共振成像(CMRA)(5.0TCS-CMRA)与3.0T使用CS的梯度回波-CMRA(3.0TCS-CMRA)的性能。资料与方法 前瞻性纳入中国医学科学院北京协和医院2023年12月16日—2024年1月14日25名23~30岁健康志愿者,接受3.0TCS-CMRA和5.0TCS-CMRA检查,间隔时间在2周内,其中3.0TCS-CMRA常规应用T2准备脉冲,5.0TCS-CMRA未应用T2准备脉冲。评估两组图像质量评分、冠状动脉长度、信噪比(SNR)和冠状动脉血流与邻近心肌或软组织之间的对比噪声比(CNRmyo-blood)等。结果 在5.0TCS-CMRA上,25名受试者右冠状动脉近段SNR和CNRmyo-blood显著高于3.0TCS-CMRA(SNR:318.07±94.06比223.81±51.19,t=-5.609,P<0.001;CNRmyo-blood:212.75±91.44比149.70±59.53,Z=-3.619,P<0.001),左前降支和左回旋支近段SNR和CNRmyo-blood未显著高于3.0TCS-CMRA(SNR:315.52±102.49比306.35±92.85,t=-0.627,P=0.536;289.72±88.79比272.87±84.68,t=-1.226,P=0.232;CNRmyo-blood:135.83±93.53比203.94±74.30,t=4.132,P<0.001;117.66±79.63比161.60±78.91,t=3.127,P=0.005)。5.0TCS-CMRA测得3大冠状动脉长度显著短于3.0TCS-CMRA[右冠状动脉:(126.04±31.54)mm比(137.20±29.93)mm,t=2.911,P=0.008;左前降支:(122.68±24.63)mm比(134.24±23.38)mm,Z=-3.026,P=0.002;左回旋支:(57.07±26.70)mm比(68.27±24.02)mm,t=2.552,P=0.018]。3.0TCS-CMRA与5.0TCS-CMRA所需扫描时间差异无统计学意义[(8.60±2.84)min比(8.30±2.32)min,Z=-0.183,P=0.855]。5.0TCS-CMRA的3大冠状动脉图像评分显著低于3.0TCS-CMRA(右冠状动脉:2.52±0.59比3.16±0.69,Z=-3.258,P=0.001;左前降支:2.72±0.74比3.24±0.66,Z=-2.540,P=0.011;左回旋支:2.44±0.71比3.00±0.87,Z=-2.462,P=0.014)。结论 在缺乏T2准备的情况下,5.0TCS-CMRA与3.0TCS-CMRA相比,在右冠状动脉近段SNR和CNRmyo-blood方面仍具有明显优势,提示5.0TCS-CMRA的应用潜力。未来,适用的T2准备脉冲或潜在的替代方案可能进一步提升5.0TCS-CMRA的性能。
Purpose To compare the 5.0T gradient echo coronary magnetic resonance angiography(CMRA)using compressed sensing(CS)acceleration technology(5.0TCS-CMRA)vs.3.0T gradient echo-CMRA(3.0TCS-CMRA)using CS.Materials and Methods Twenty-five healthy volunteers aged 23 to 30 years from December 16,2023 to January 14,2024 at Peking Union Medical College Hospital,Chinese Academy of Medical Sciences were prospective enrolled in this study.The interval between 3.0TCS-CMRA and 5.0TCS-CMRA was within two weeks.3.0TCS-CMRA used T2 preparation and 5.0TCS-CMRA did not use T2 preparation.The image quality scores,coronary artery length,signal-to-noise ratio(SNR)and contrast-to-noise ratio between coronary blood and adjacent myocardium or tissue(CNRmyo-blood)were evaluated.Results On 5.0TCS-CMRA,the SNR and CNRmyo-blood of the proximal right coronary artery(RCA)in 25 healthy volunteers were significantly higher than those of 3.0TCS-CMRA(SNR:318.07±94.06 vs.223.81±51.19,t=-5.609,P<0.001;CNRmyo-blood:212.75±91.44 vs.149.70±59.53,Z=-3.619,P<0.001),while the SNR and CNRmyo-blood of proximal left anterior descending coronary artery(LAD)and left circumflex coronary artery(LCX)were not significantly higher than those of 3.0TCS-CMRA(SNR:315.52±102.49 vs.306.35±92.85,t=-0.627,P=0.536;289.72±88.79 vs.272.87±84.68,t=-1.226,P=0.232;CNRmyo-blood:135.83±93.53 vs.203.94±74.30,t=4.132,P<0.001;117.66±79.63 vs.161.60±78.91,t=3.127,P=0.005).The length of the three coronary arteries measured by 5.0TCS-CMRA was significantly shorter than that of 3.0TCS-CMRA[RCA:(126.04±31.54)mm vs.(137.20±29.93)mm,t=2.911,P=0.008;LAD:(122.68±24.63)mm vs.(134.24±23.38)mm,Z=-3.026,P=0.002;LCX:(57.07±26.70)mm vs.(68.27±24.02)mm,t=2.552,P=0.018].There was no significant difference in the scanning time required between 3.0TCS-CMRA and 5.0TCS-CMRA[(8.60±2.84)min vs.(8.30±2.32)min,Z=-0.183,P=0.855].The image scores of the three major coronary arteries of 5.0TCS-CMRA were significantly lower than those of 3.0TCS-CMRA(RCA:2.52±0.59 vs.3.16±0.69,Z=-3.258,P=0.001;LAD:2.72±0.74 vs.3.24±0.66,Z=-2.540,P=0.011;LCX:2.44±0.71 vs.3.00±0.87,Z=-2.462,P=0.014).Conclusion In the absence of T2 preparation,5.0TCS-CMRA can still show obvious advantages in the SNR and CNRmyo-blood of proximal RCA compared with 3.0TCS-CMRA,which suggests the application potential of 5.0TCS-CMRA.In the future,a suitable T2 preparation pulse or potential alternative may significantly improve the performance of the 5.0TCS-CMRA.
作者
赵士海
徐峥雨
郭玉博
孙淦
林路
王怡宁
ZHAO Shihai;XU Zhengyu;GUO Yubo;SUN Gan;LIN Lu;WANG Yining(Chinese Academy of Medical Sciences and Peking Union Medical College,Department of Radiology,Peking Union Medical College Hospital,Beijing 100730,China;不详)
出处
《中国医学影像学杂志》
北大核心
2025年第7期706-711,共6页
Chinese Journal of Medical Imaging
基金
国家杰出青年科学基金(82325026)
国家自然科学基金重点国际合作研究项目(82020108018)
中国医学科学院临床与转化医学研究专项项目(2023-I2M-CT-A-004)
中国医学科学院中央级公益性科研院所基本科研业务费专项资金资助(2024-RC320-03)
北京协和医院中央高水平医院临床科研专项项目(2022-PUMCH-B-027)。
关键词
磁共振成像
超高场强
冠状动脉磁共振成像
压缩感知
志愿者
Magnetic resonance imaging
Ultra-high field
Coronary magnetic resonance angiography
Compressed sensing
Volunteers
