摘要
目的:深入认识白族药用植物倒钩刺的化学成分。方法:采用硅胶柱层析、MCI柱层析、Sephadex LH-20凝胶柱层析等色谱手段对倒钩刺95%乙醇提取物的化学成分进行分离纯化,依据理化性质和现代波谱分析技术对化合物进行结构鉴定。结果:从倒钩刺全草95%乙醇提取物二个不同极性部位分离纯化了10个单体化合物,分别鉴定为β-谷甾醇乙酸酯(1)、豆甾-4-烯-3-酮(2)、蔷薇酸(3)、山柰酚(4)、雪松醇(5)、agrimonolide(6)、补骨脂素(7)、莳萝油脑(8)、正二十烷(9)、正三十二烷-1-醇(10)。结论:化合物1、2、5、8-10为首次从该植物中分离得到。
Objective To gain a deeper understanding thechemical constituents of Bai ethnic medicinal plant“Dao-Gou-Ci”(Rubus delavayi).Methods The chemical constituents from 95%ethanol extract of Rubus delavayi were isolated and purified by repeated column chromatography with silicagel,MCI,and Sephadex LH-20,and their structures were identified by the comprehensive analysis of physicochemical properties and spectral data.Results Ten monomeric compounds were isolated and purified from two different polar fractions of the 95%ethanol extract of R.delavayi whole plant,and identified asβ-sitosterol acetate(1),stigmast-4-en-3-one(2),euscaphic acid(3),kaempferol(4),cedar alcohol(5),agrimonolide(6),psoralen(7),dillapiole(8),n-eicosane(9),and 1-dotriacontanol(10).Conclusion Compounds 1,2,5,and 8-10 were isolated from R.delavayi for the first time.
作者
韩文萱
郝艺
徐伟
罗晓磊
王敏
肖朝江
姜北
HAN Wenxuan;HAO Yi;XU Wei;LUO Xiaolei;WANG Min;XIAO Chaojiang;JIANG Bei(Yunnan Key Laboratory of Screening and Research on Anti-Pathogenic Plant Resources from Western Yunnan,Dali 671000,China;College of Pharmacy&Institute of Materia Medica,Dali University,Dali 671000,China)
出处
《中国民族民间医药》
2025年第15期52-56,共5页
Chinese Journal of Ethnomedicine and Ethnopharmacy
基金
云南省滇西抗病原植物资源筛选研究重点实验室建设项目(202305AG340015)
大理州科技计划项目(D2019NA02)
云南省滇西抗病原植物资源筛选研究重点实验室开放课题研究生项目(APR2023Y01)
云南省教育厅科学研究基金项目(2024Y862)。
关键词
白族药
倒钩刺
化学成分
分离鉴定
Bai Ethnic Medicinal Plant
Rubus delavayi Franch.
Chemical Constituents
Isolation and Identification
