摘要
目的探究全程营养管理对牛奶蛋白过敏(cow milk protein allergy,CMPA)患儿生长发育和营养状况的影响。方法选取2019年3月至2020年3月于南宁市第八人民医院及宾阳县人民医院、马山县人民医院、武鸣区妇幼保健医院、宾阳县妇幼保健院、上林县人民医院、上林县妇幼保健院、横县人民医院儿科首次接诊并确诊的377例年龄≤1岁CMPA患儿作为研究对象,采用随机抽签法分为实验组(n=187)与对照组(n=190)。对照组进行非全程营养干预,实验组进行全程营养干预。比较两组发育情况、营养指标及体格生长情况。结果干预后,实验组身长别体质量Z评分、年龄别身高Z评分均高于对照组,营养不良发生率低于对照组,差异有统计学意义(P<0.05)。干预后,两组血清锌、铁蛋白、前白蛋白、视黄素结合蛋白水平均高于干预前,且实验组血清锌、铁蛋白、视黄素结合蛋白水平均高于对照组(P<0.05),但两组前白蛋白水平比较差异无统计学意义;两组干预前后组内、组间白蛋白水平比较差异无统计学意义。实验组生长迟缓占比低于对照组,发育正常占比高于对照组,差异有统计学意义(P<0.05),两组超前生长占比比较差异无统计学意义。结论全程营养管理可有效减少CMPA患儿营养不良的发生,促进患儿生长发育,值得临床推广应用。
Objective To explore the effects of comprehensive nutritional management on the growth and nutritional status of children with cow milk protein allergy(CMPA).Methods A total of 377 children with CMPA≤1 year old who were first admitted and diagnosed in the Pediatrics department of the Nanning Eighth People's Hospital,Binyang County People's Hospital,Mashan County People's Hospital,Wuming District Maternal and Child Health Hospital,Binyang County Maternal and Child Health Hospital,Shanglin County People's Hospital,Shanglin County Maternal and Child Health Hospital and Hengxian County People's Hospital from March 2019 to March 2020 were selected as the research subjects,they were divided into the experimental group(n=187)and the control group(n=190)by random drawing method.The control group had a non-comprehensive nutritional intervention and the experimental group had a comprehensive nutritional intervention.The development,nutritional indicators and physical growth were compared between the two groups.Results After intervention,weight for height Z score and height for age Z score in the experimental group were higher than those in the control group,and the incidence of malnutrition was lower than that in the control group,the differences were statistically significant(P<0.05).After intervention,the levels of serum zinc,ferritin,proalbumin and retinotein-binding protein of the two groups were higher than before intervention,and the levels of serum zinc,ferritin and retinotein-binding protein in the experimental group were higher than those in the control group(P<0.05),but there was no statistically significant difference in the levels of proalbumin between the two groups;there were no significant differences in albumin level within and between the two groups before and after intervention.The percentage of growth retardation in the experimental group was lower than that in the control group,the percentage of normal development was higher than that in the control group,the differences were statistically significant(P<0.05),and there was no difference significant in the percentage of overgrowth between the two groups.Conclusion Comprehensive nutritional management can effectively reduce the occurrence of malnutrition in children with CMPA,promote the growth and development of children,it is worthy of clinical promotion and application.
作者
王兆康
黄淑清
黄德恩
黄联飞
黎海英
WANG Zhaokang;HUANG Shuqing;HUANG De'en;HUANG Lianfei;LI Haiying(Department of Pediatrics,Ruikang Hospital affiliated to Guangxi University of Chinese Medicine,Nanning,Guangxi,530001,China;Department of Pediatrics,Nanning Eighth People's Hospital,Nanning,Guangxi,530001,China;Department of Neonatology,Wuming District Maternal and Child Health Care Hospital,Nanning,Guangxi,530100,China;Department of Pediatrics,Mashan County People's Hospital,Nanning,Guangxi,530600,China;Department of Pediatrics,Binyang People's Hospital,Nanning,Guangxi,530405,China)
出处
《当代医学》
2025年第4期82-86,共5页
Contemporary Medicine
基金
广西卫生健康委员会计划课题(Z20190286)。
关键词
牛奶过敏
全程营养管理
患儿
Cow milk protein allergy
Comprehensive nutritional management
Children
