摘要
目的 分析身痛逐瘀汤加减方联合颈椎牵引治疗气滞血瘀型神经根型颈椎病临床疗效。方法 纳入150例神经根型颈椎病患者,随机分为对照组(颈椎牵引)与观察组(身痛逐瘀汤加减方+颈椎牵引),干预周期4周。评估2组中医证候积分、疼痛程度(VAS)、颈椎功能障碍指数(NDI)、田中靖久颈椎病症状量表20分法(TJK-20)、肌电图参数、白介素细胞-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(hs-CRP)变化,统计临床疗效与安全性。结果 观察组治疗后中医证候积分、VAS评分、NDI评分、F波潜伏期(C6、C7)、IL-6、TNF-α、hs-CRP水平低于对照组(P<0.05);TJK-20评分、MCV(尺神经、正中神经)速度高于对照组(P<0.05);观察组总有效率92.00%高于对照组76.00%(P< 0.05),2组均未出现不良反应。结论 身痛逐瘀汤加减方联合颈椎牵引治疗气滞血瘀型神经根型颈椎病,能够显著缓解疼痛与功能障碍,抑制局部与全身炎症反应,促进神经根功能恢复,且安全性良好。
Objective To analyze the efficacy of modified Shentong Zhuyu Decoction combined with cervical traction in the treatment of cervical spondylotic radiculopathy(CSR)with the syndrome of qi stagnation and blood stasis.Methods A total of 150 patients with CSR(from September 2021 to September 2024)were randomly divided into a control group(cervical traction)and an observation group(modified Shentong Zhuyu Decoction+cervical traction),with a 4-week intervention period.The changes in the TCM syndrome scores,pain intensity(VAS),Neck Disability Index(NDI),scores of TJK-20 Cervical Spondylosis Symptom Scale,electromyographic(EMG)parameters,levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-a),and high-sensitivity C-reactive protein(hs-CRP)were evaluated,and the clinical efficacy and safety were statistically analyzed.Results After treatment,the observation group showed significantly lower TCM syndrome scores,VAS scores,NDI scores,F-wave latency(C6,C7),levels of IL-6,TNF-α,and hs-CRP compared to the control group(P<0.05).The TJK-20 scores and motor conduction velocity(MCV)of the ulnar and median nerves were significantly higher in the observation group(P<0.05).The total effective rate in the observation group was 92.0%,significantly higher than 76.0%in the control group(P<0.05).No adverse reactions occurred in either group.Conclusion Modified Shentong Zhuyu Decoction combined with cervical traction significantly alleviates pain and dysfunction,inhibits local and systemic infammatory responses,promotes nerve root functional recovery,and demonstrates good safety in treating CSR with the syndrome of qi stagnation and blood stasis.
作者
赵文霞
杨祥军
袁晖戍
姜益常
ZHAO Wenxia;YANG Xiangjun;YUAN Huishu;JIANG Yichang(Heilongjiang University of Chinese Medicine,Harbin 150040,China;The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150001,China;The First Affliated Hospital of Heilongjiang University of Chinese Medicine,Harbin 150040,China)
出处
《吉林中医药》
2025年第8期936-940,共5页
Jilin Journal of Chinese Medicine
基金
黑龙江省中医药科研项目(ZHY2022-189)。
关键词
神经根型颈椎病
气滞血瘀型
身痛逐瘀汤加减方
颈椎牵引
疼痛
功能障碍
炎症反应
cervical spondylotic radiculopathy
syndrome of qi stagnation and blood stasis
modified Shentong Zhuyu Decoction
cervical traction
pain
dysfunction
inflammatory response
