摘要
血管迷走性晕厥是儿童和青少年最常见的晕厥类型,其发生涉及自主神经调节失衡、血流动力学异常及神经体液因素等多系统的交互作用。近年来,生物标志物在儿童血管迷走性晕厥的诊断、分型和治疗评估中展现出重要价值,其潜在的生物标志物包括儿茶酚胺、抗利尿激素、血清铁、铁蛋白及血常规参数、维生素D等,这些生物标志物可能参与自主神经调节失衡、血管张力异常等关键病理环节。系统分析这些生物标志物有助于优化血管迷走性晕厥的诊断策略和干预措施,并为进一步研究提供方向。
Vasovagal syncope is the most common type of syncope in children and adolescents.Its occurrence involves the interaction of multiple systems such as autonomic nerve regulation imbalance,hemodynamic abnormalities,and neurohumoral factors.In recent years,biomarkers have demonstrated significant value in the diagnosis,classification and treatment evaluation of vasovagal syncope in children.The potential biomarkers include catecholamines,antidiuretic hormone,serum iron,ferritin and blood routine parameters,vitamin D,etc.These biomarkers may be involved in key pathological links such as autonomic nerve regulation imbalance and abnormal vascular tension.Systematic analysis of these biomarkers is helpful for optimizing the diagnostic strategies and intervention measures of vasovagal syncope,and providing directions for further research.
作者
武文娟
李淑芬
WU Wenjuan;LI Shufen(Department of Pediatrics,the Second Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,China;Department of Pediatrics,People′s Hospital of Xinjiang Uygur Autonomous Region,Urumqi 830000,China)
出处
《医学综述》
2025年第15期1847-1850,1857,共5页
Medical Recapitulate