摘要
目的 探讨“通督温阳”法针刺治疗儿童遗尿症(NE)的临床疗效,以期为临床治疗提供参考。方法 选取南京中医药大学附属医院在2022年1月—2024年1月收治的80例NE患儿为研究对象。采用随机数字表法将患儿分成A组和B组,每组40例。A组患儿采取常规治疗。B组患儿在A组治疗基础上给予“通督温阳”法针刺治疗。比较2组患儿治疗前、治疗4周时中医证候积分、尿流率、膀胱容量、残余尿量及抗利尿激素(ADH)水平;比较2组患儿治疗4周时的临床疗效、治疗期间不良反应发生情况及短期预后(随访3个月时的复发情况)。结果 治疗前,2组患儿主、次证积分及证候总积分比较,差异无统计学意义(P>0.05);治疗后,2组患儿主、次证积分及证候总积分均低于治疗前,且B组低于A组,差异均有统计学意义(P<0.05)。B组患儿治疗总有效率高于A组,差异有统计学意义(P<0.05)。治疗前,2组患儿尿流率、膀胱容量和残余尿量比较,差异无统计学意义(P>0.05);治疗后,2组患儿尿流率、膀胱容量均大于治疗前,且B组均大于A组,差异均有统计学意义(P<0.05);治疗后,2组患儿残余尿量均少于治疗前,且B组少于A组,差异均有统计学意义(P<0.05)。治疗前,2组患儿ADH水平比较,差异无统计学意义(P>0.05);治疗后,2组患儿ADH水平均高于治疗前,且B组高于A组,差异均有统计学意义(P<0.05)。2组患儿不良反应发生率比较,差异无统计学意义(P>0.05);随访3个月,B组患儿复发率低于A组,差异有统计学意义(P<0.05)。结论 “通督温阳”法针刺治疗NE患儿疗效确切,可改善患儿临床症状,提高膀胱功能和血清ADH水平,短期预后较好,具有一定安全性。
Objective To investigate the clinical efficacy of Tongdu Wenyong(Unblocking the Governor Vessel and Warming Yang)acupuncture for children with nocturnal enuresis(NE),aiming to provide references for clinical treatment.Methods Eighty pediatric patients with NE admitted to the Affiliated Hospital of Nanjing University of Chinese Medicine from January 2022 to January 2024 were selected.Using random number assignment,children were allocated to Group A(n=40)receiving conventional treatment and Group B(n=40)receiving additional Tongdu Wenyong acupuncture.Traditional Chinese Medicine(TCM)symptom scores,urine flow rate,bladder capacity,residual urine volume,and antidiuretic hormone(ADH)levels were compared before treatment and at 4 weeks of treatment.Clinical efficacy at 4 weeks,adverse reactions during treatment,and short-term prognosis(recurrence rate at the 3-month follow-up)were compared.Results Before treatment,no significant differences existed in primary symptom scores,secondary symptom scores,or total TCM symptom scores between groups(P>0.05);after treatment,all symptom scores decreased in both groups compared to pre-treatment levels,with Group B showing significantly lower scores than Group A(P<0.05).The overall response rate was significantly higher in Group B than in Group A(P<0.05).Before treatment,no significant differences were noted in urine flow rate,bladder capacity,or residual urine volume between groups(P>0.05);after treatment,urine flow rate and bladder capacity increased in both groups compared to pre-treatment levels,with Group B showing significantly higher values than Group A(P<0.05);residual urine volume decreased in both groups compared to pre-treatment levels,with Group B showing significantly lower values than Group A(P<0.05).Before treatment,no significant difference was observed in ADH levels between groups(P>0.05);after treatment,ADH levels increased in both groups compared to pre-treatment levels,with Group B showing significantly higher levels than Group A(P<0.05).No significant difference was noted in adverse reaction rates between groups(P>0.05).At 3-month follow-up,the recurrence rate was significantly lower in Group B than in Group A(P<0.05).Conclusion Tongdu Wenyong acupuncture demonstrates definite efficacy for pediatric children with NE,ameliorating clinical symptoms,enhancing bladder function and serum ADH levels,with favorable short-term prognosis and acceptable safety profiles.
作者
李彦彩
鲍超
陈栋
李建兵
王楠
屠路亭
原萌谦
Li Yancai;Bao Chao;Chen Dong;Li Jianbing;Wang Nan;Tu Luting;Yuan Mengqian(Department of Acupuncture and Rehabilitation,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China;Department of Rehabilitation,Wuxi No.2 Chinese Medicine Hospital,Wuxi Jiangsu 214121,China)
出处
《保健医学研究与实践》
2025年第4期82-86,100,共6页
Health Medicine Research and Practice
基金
江苏省中医药管理局科技项目(FY201701)
江苏省中医药科技发展面上项目(MS2022025)。
关键词
遗尿症
“通督温阳”法针刺
临床疗效
膀胱功能
儿童
Nocturnal enuresis
Tongdu Wenyong acupuncture
Clinical efficacy
Bladder function
Children
