摘要
Dear Editor,For the past few decades,mosquito-borne orthoflaviviruses,such as dengue virus,Zika virus,and West Nile virus(WNV),have posed significant threats to global public health.The Orthoflavivirus genus comprises more than 70 viruses,many of which are responsible for a wide range of diseases in humans and animals,including febrile illnesses,encephalitis,and hemorrhagic febrile illness.These viruses are associated with approximately 400 million infections and 100 million symptomatic cases worldwide each year(Van Leur et al.,2021).Among them,Usutu virus(USUV)is an emerging pathogen classified alongside WNV within the Japanese encephalitis virus(JEV)serogroup of the Orthoflavivirus genus,the Flaviviridae family.USUV has spread from Africa to Europe since the late 20th century.It primarily causes central nervous system disorders in birds,with several large-scale mortality events recorded in Europe.USUV can also infect humans,it typically leads to neurological complications in rare cases(Roesch et al.,2019).
基金
funded by grants from the National Key Research and Development Program of China(2022YFD1801900)
National Natural Science Foundation of China(32272976&32302848)
Sichuan Provincial Department of Science and Technology international scientific and technological innovation cooperation(2022YFH0026)
the earmarked fund for China Agricultural Research System(CARS-42-17)
Program Sichuan Veterinary Medicine and Drug Innovation Group of China Agricultural Research System(SCCXTD-2021-18)
the Innovation and Demonstration of Industry and Education Integration in Feed Industrial Chain Transformation and Upgradation,Sichuan Province,China.
