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不同硬膜外分娩镇痛方式对产妇产时发热及妊娠结局的影响研究

Study on the Impact of Different Epidural Labor Analgesia Methods on Intrapartum Fever and Pregnancy Outcomes
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摘要 探讨不同硬膜外分娩镇痛方式对产妇产时发热及妊娠结局的影响。选取120例于2023年1月—2024年12月在浙江大学医学院附属第一医院产科接受硬膜外分娩镇痛的产妇为研究对象,根据镇痛方式的不同将其分为氢吗啡酮组和罗哌卡因组,每组各60例。比较两组产妇的镇痛效果、产时发热情况、妊娠结局等。结果显示,氢吗啡酮组在宫口全开、胎儿娩出后、胎盘娩出后1 h的疼痛视觉模拟评分、产时发热率低于罗哌卡因组,不良反应发生率高于罗哌卡因组,差异具有统计学意义(P<0.05)。两组的各个产程所用时间、剖宫产率、新生儿窒息率无统计学差异(P>0.05)。根据产妇是否发热将其分为发热组与非发热组,与非发热组相比,发热组分娩后的WBC、CRP水平更高,差异具有统计学意义(P<0.05)。研究发现,采用氢吗啡酮硬膜外镇痛能减轻分娩时的疼痛,减少产时发热情况的出现,且对产程和新生儿结局无影响,但其不良反应发生率高于罗哌卡因,应积极预防和控制。 This study explores the impact of different epidural labor analgesia methods on intrapartum fever and pregnancy outcomes.A total of 120 parturients who received epidural labor analgesia in the Obstetrics Department of The First Affiliated Hospital of Zhejiang University Medical College from January 2023 to December 2024 were selected as research subjects.They were divided into the hydromorphone group and the ropivacaine group according to different analgesia methods,with 60 cases in each group.The analgesic effect,intrapartum fever,and pregnancy outcomes were compared between the two groups.The results showed that the visual analog scale(VAS)scores for pain at full cervical dilation,after fetal delivery,and 1 hour after placental delivery,as well as the intrapartum fever rate in the hydromorphone group were lower than those in the ropivacaine group,while the incidence of adverse reactions was higher,with statistically significant differences(P<0.05).There were no statistically significant differences in the duration of each stage of labor,cesarean section rate,or neonatal asphyxia rate between the two groups(P>0.05).When parturients were divided into the fever group and the non-fever group based on the presence of fever,the levels of white blood cells(WBC)and C-reactive protein(CRP)after delivery in the fever group were significantly higher than those in the non-fever group(P<0.05).The study found that hydromorphone-based epidural analgesia can relieve labor pain,reduce intrapartum fever,and has no impact on the labor process or neonatal outcomes.However,its incidence of adverse reactions is higher than that of ropivacaine,requiring active prevention and control.
作者 钟玉珊 Zhong Yushan(The First Affiliated Hospital Zhejiang University Medical College,Hangzhou,Zhejiang 311121)
出处 《科技与健康》 2025年第13期81-84,共4页 Technology and Health
关键词 硬膜外分娩镇痛 产妇 产时发热 妊娠结局 epidural labor analgesia parturient intrapartum fever pregnancy outcomes
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