摘要
目的分析宫颈胃型腺癌(G-EAC)与普通型宫颈腺癌(UEA)的诊疗特征及预后特点。方法以2019年1月-2023年12月天津港口医院收治的行广泛全子宫切除术的G-EAC患者29例及UEA患者51例为研究对象,比较G-EAC患者与UEA患者的诊疗特征(临床表现、病理检查)与预后情况(疾病进展、复发、转移、死亡)。结果G-EAC患者阴道排液、宫颈肿大占比多于UEA患者(P<0.05);G-EAC患者HPV阳性占比少于UEA患者,而FIGO分期>Ⅱ期、肿瘤直径>4 cm、宫颈浸润深度外1/3、淋巴结转移、宫体浸润、神经侵犯、卵巢转移占比多于UEA患者(P<0.05);G-EAC患者疾病进展、转移发生率高于UEA患者(P<0.05)。结论G-EAC与UEA患者在诊疗特征、预后情况方面存在较大差异,临床可参考其临床表现、病理检查,完善疾病的早期筛查与鉴别。
Objective To analyze the diagnostic,therapeutic,and prognostic characteristics of gastric-type endocervical adenocarcinoma(G-EAC)and usual-type endocervical adenocarcinomas(UEA).Methods A total of 29 patients with G-EAC and 51 patients with UEA who underwent extensive hysterectomy in Tianjin Port Hospital from January 2019 to December 2023 were selected as the research objects.The diagnosis and treatment characteristics(clinical manifestations,pathological examination)and prognosis(disease progression,recurrence,metastasis and death)of G-EAC patients and UEA patients were compared.Conclusion:There are significant differences in diagnosis and treatment characteristics and prognosis between G-EAC and UEA patients.Results The proportion of vaginal discharge and cervical enlargement in G-EAC patients was higher than that in UEA patients(P<0.05).The proportion of HPV positive in G-EAC patients was less than that in UEA patients,while the proportion of FIGO stage>Ⅱ,tumor diameter>4 cm,outer 1/3 of cervical infiltration depth,lymph node metastasis,uterine body infiltration,nerve invasion and ovarian metastasis was more than that in UEA patients(P<0.05).The incidence of disease progression and metastasis in G-EAC patients was higher than that in UEA patients(P<0.05).Conclusion There are great differences in the diagnosis and treatment characteristics and prognosis between G-EAC and UEA patients.The clinical manifestations and pathological examination can be referred to improve the early screening and identification of the disease.
作者
孟媛
MENG Yuan(Department of Gynecology and Obstetrics,Tianjin Port Hospital,Tianjin 300456,China)
出处
《医学信息》
2025年第16期140-143,共4页
Journal of Medical Information
关键词
宫颈胃型腺癌
普通型宫颈腺癌
人乳头状瘤病毒
临床表现
病理检查
预后
Gastric-type endocervical adenocarcinoma
Usual-type endocervical adenocarcinomas
Human papillomavirus
Clinical manifestations
Pathological examination
Prognosis
