摘要
目的分析瑞马唑仑复合舒芬太尼方案在内镜逆行胰胆管造影术(endoscopic retrograde cholangiopan-creatography,ERCP)中的应用效果。方法方便选取2022年12月—2023年12月贵州省兴义市人民医院的68例接受ERCP治疗患者为研究对象,按照不同麻醉方式分为两组,每组34例。对照组使用丙泊酚复合舒芬太尼为麻醉方案;观察组使用瑞马唑仑复合舒芬太尼为麻醉方案。比较两组患者生理指标、疼痛评分、麻醉苏醒指标及不良反应发生率。结果观察组在麻醉5 min、进镜时、手术开始10 min与术毕时的心率与平均动脉压低于对照组,差异均有统计学意义(P均<0.05)。观察组术后6、12、24 h时疼痛评分分别为(3.03±0.13)分、(2.43±0.64)分、(2.68±0.11)分,均低于对照组的(3.96±0.07)分、(3.01±0.22)分、(3.14±0.15)分,差异均有统计学意义(t=6.728,4.997,14.420;P均<0.05)。观察组麻醉苏醒时间为(18.89±2.07)min,术后定向力恢复时间为(7.28±1.01)min,均短于对照组的(30.42±2.06)min、(10.14±1.08)min,差异均有统计学意义(t=23.021,11.278;P均<0.05)。观察组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论在ERCP治疗中,瑞马唑仑复合舒芬太尼具有良好的应用表现,有助于缓解患者疼痛感受与生理指标异常情况,有利于减少麻醉苏醒时间与定向力恢复时间,可加强对各类术中不良反应与术后不良反应的防护效果。
Objective To analyze the application effect of remimazolam combined with sufentanil in endoscopic retro-grade cholangiopancreatography(ERCP).Methods A total of sixty-eight patients undergoing ERCP treatment in Xin-gyi People′s Hospital,Guizhou Province from December 2022 to December 2023 were conveniently selected as the re-search objects and divided into two groups according to different anesthesia methods,with thirty-four cases in each group.The control group received propofol combined with sufentanil as the anesthesia protocol,while the observation group received remimazolam combined with sufentanil.Physiological indicators,pain scores,anesthesia recovery indi-cators,and the incidence of adverse reactions were compared between the two groups.Results The heart rate and mean arterial pressure of the observation group at 5 minutes after anesthesia,during scope insertion,10 minutes after surgery initiation,and at the end of surgery were lower than those of the control group,differences were statistically significant(all P<0.05).The pain scores of the observation group at 6,12,and 24 h after surgery were 3.03±0.13,2.43±0.64,and 2.68±0.11,which were lower than 3.96±0.07,3.01±0.22,3.14±0.15 of the control group,differences were statistically significant(t=6.728,4.997,14.420;all P<0.05).The anesthesia recovery time of the observation group was(18.89±2.07)min,and the postoperative orientation recovery time was(7.28±1.01)min,both shorter than(30.42±2.06)min,(10.14±1.08)min of the control group,differences were statistically significant(t=23.021,11.278;all P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion In ERCP treatment,remimazolam combined with suf-entanil demonstrates good application performance,helping to relieve patients′pain and abnormal physiological indi-cators,shorten anesthesia recovery time and orientation recovery time,and strengthen the prevention of various intra-operative and postoperative adverse reactions.
作者
李敏
LI Min(Department of Anesthesiology,Xingyi People′s Hospital,Guizhou Province,Xingyi 562400,Guizhou,China)
出处
《系统医学》
2025年第12期48-51,共4页
Systems Medicine
关键词
瑞马唑仑
舒芬太尼
内镜逆行胰胆管造影术
麻醉
Remimazolam
Sufentanil
Endoscopic retrograde cholangiopancreatography
Anesthesia
