摘要
分析1例敌草快(DQ)中毒致横纹肌溶解患者的临床资料。该患者服用DQ后出现以腹泻为主的消化道症状,2 d后出现双下肢非凹陷性水肿伴疼痛,检测肌酸激酶(CK)明显升高。给予连续性肾脏替代治疗(CRRT)5次,后因经济原因中断治疗,2年后随访遗留下肢水肿。检索多个数据库获得5篇文献,报道9例DQ中毒致横纹肌溶解病例,临床表现多样,以无尿或少尿以及下肢水肿为主,CK升高,病死率高。DQ中毒致横纹肌溶解尚无特效解毒剂及有效治疗方法,早期血液净化治疗可改善预后。
Analysis of the clinical data of a patient with rhabdomyolysis caused by diquat(DQ)poisoning.After ingesting DQ,the patient presented with gastrointestinal symptoms mainly characterized by diarrhea.Two days later,non-pitting edema of both lower limbs with pain,and the creatine kinase(CK)was significantly increased.After continuous renal replacement therapy(CRRT)was given,the treatment was discontinued due to economic reasons,during the follow-up two-year later,lower limb edema remained.Five articles were retrieved from multiple databases,which reported nine cases of rhabdomyolysis caused by DQ poisoning.Clinical manifestations varied and mainly included oliguria or anuria and lower limb edema,elevated CK levels and high mortality.There is no specific antidote and effective treatment for rhabdomyolysis caused by DQ poisoning.Early blood purification therapy may improve prognosis.
作者
顾亮
孙明
吴超
翟恒
GU Liang;SUN Ming;WU Chao;ZHAI Heng(Emergency Medicine Department of the Affiliated Suqian Hospital of Xuzhou Medical University,Suqian,Jiangsu 223800,China;不详)
出处
《中国工业医学杂志》
2025年第3期303-305,共3页
Chinese Journal of Industrial Medicine
基金
宿迁市科技局项目(Z2022108)。
