摘要
目的探讨改良手法复位联合盐酸倍他司汀氯化钠治疗不典型良性阵发性位置性眩晕(benign paroxysmal positional vertigo,BPPV)的临床疗效。方法选取2020年3月至2023年3月抚州市中医医院收治的70例不典型BPPV患者作为研究对象,采用简单随机化方法分为对照组与观察组,每组35例。对照组行改良手法复位治疗,观察组行改良手法复位联合盐酸倍他司汀氯化钠治疗。比较两组临床疗效、椎基底动脉平均血流速度(mean velocity,Vm)、眩晕障碍量表(dizziness handicap inventory,DHI)、眩晕前庭症状指数(vestibular symptom index,VSI)、Berg平衡量表(Berg balance scale,BBS)、计时平衡试验及复发率。结果观察组治疗总有效率为91.43%,高于对照组的71.43%,差异有统计学意义(P<0.05)。治疗后,两组左侧椎动脉、右侧椎动脉、基底动脉Vm均快于治疗前,且观察组快于对照组,差异有统计学意义(P<0.05)。治疗后,两组功能、情感、躯体评分及总分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,两组VSI评分均低于治疗前,BBS评分均高于治疗前,计时平衡试验均长于治疗前,且观察组VSI评分低于对照组,BBS评分高于对照组,计时平衡试验长于对照组,差异有统计学意义(P<0.05)。治疗后1个月,两组复发率比较差异无统计学意义;治疗后3、6个月,观察组复发率均低于对照组,差异有统计学意义(P<0.05)。结论改良手法复位联合盐酸倍他司汀氯化钠治疗不典型BPPV疗效显著,可改善平衡能力,促进眩晕症状缓解,减少复发。
Objective To explore the clinical efficacy of modified manual reduction combined with betahistine hydrochloride and sodium chloride in the treatment atypical benign paroxysmal positional vertigo(BPPV).Methods A total of 70 patients with atypical BPPV admitted to Fuzhou Hospital of Traditional Chinese Medicine from March 2020 to March 2023 were selected as the research subjects,they were randomly divided into the control group and the observation group,with 35 cases in each group.The control group was treated by modified manual reduction,and the observation group was treated by modified manual reduction combined with betahistine hydrochloride and sodium chloride.The clinical efficacy,vertebrobasilar artery blood flow mean velocity(Vm),dizziness handicap inventory(DHI),vestibular symptom index(VSI),Berg balance scale(BBS),timing balance test and recurrence rate were compared between the two groups.Results The total effective rate of treatment in the observation group was 91.43%,which was higher than 71.43%in the control group,and the difference was statistically significant(P<0.05).After treatment,the Vm of left vertebral artery,right vertebral artery and basilar artery of the two groups were faster than before treatment,and the observation group was faster than the control group,the differences were statistically significant(P<0.05).After treatment,the functional,emotional and physical scores and total scores of the two groups were lower than before treatment,and the observation group was lower than the control group,the differences were statistically significant(P<0.05).After treatment,the VSI score of the two groups were lower than before treatment,and the BBS score were higher than before treatment,and timing balance test were longer than before treatment,and the VSI score in the observation group was lower than that in the control group,the BBS score was higher than that in the control group,and timing balance test was longer than that in the control group,the differences were statistically significant(P<0.05).One month after treatment,there was no significant difference in the recurrence rate between the two groups;at 3 and 6 months after treatment,the recurrence rate in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Modified manual reduction combined with betahistine hydrochloride and sodium chloride is effective in the treatment of atypical BPPV,which can improve the balance ability,promote the relief of vertigo symptoms and reduce the recurrence.
作者
曾永娟
王强
饶璐
ZENG Yongjuan;WANG Qiang;RAO Lu(Department of Pharmacy,Fuzhou Hospital of Traditional Chinese Medicine/Affiliated Hospital of Jiangxi College of Traditional Chinese Medicine,Fuzhou,Jiangxi,344000,China;Department of Rehabilitation,Fuzhou Hospital of Traditional Chinese Medicine/Affiliated Hospital of Jiangxi College of Traditional Chinese Medicine,Fuzhou,Jiangxi,344000,China)
出处
《当代医学》
2025年第2期16-20,共5页
Contemporary Medicine
关键词
改良手法复位
盐酸倍他司汀氯化钠
不典型良性阵发性位置性眩晕
Modified reduction
Betastatin hydrochloride and sodium chloride
Atypical benign paroxysmal positional vertigo
