摘要
目的探究临床药师对抗菌药物不合理用药的药学干预效果及应用价值。方法基于院信息管理系统,对干预前(2022年9月~2023年8月)和干预后(2023年9月~2024年8月)的抗菌药物使用情况进行统计分析。分别于干预前、干预后的时间内各随机选取200份抗菌药物治疗录,以对其进行专题评述,并对不合理使用情况进行分类统计。比较观察干预前后抗菌药物销售额、DDDs和DUI的变化情况以及不合理处方的发生率。结果干预后主要抗菌药物销售额明显低于干预前,下降幅度4.72%,其中抗菌药物针剂下降明显,占比下降10.07个百分点。干预后抗菌药物平均使用强度45.26DDDs明显低于干预前的60.72DDDs(P<0.01)。干预后主要抗菌药物的平均DUI 0.628明显小于干预前0.938(P<0.05),主要抗菌药物不合理用药问题及风险明显下降。干预后不合格处方发生率2.00%明显小于干预前的16.50%(P<0.05)。结论临床药师对抗菌药物不合理用药的药学干预效果显著,可有效降低不合理用药的发生率,及抗菌药物的使用强度等,具有显著的应用价值。
OBJECTIVE To explore the pharmacological intervention effect and application value of clinical pharmacists on irrational use of antibiotics.METHODS Based on the hospital information management system,statistical analysis was conducted on the use of antibiotics before intervention(September 2022 to August 2023)and after intervention(September 2023 to August 2024).Randomly select 200 records of antibiotic treatment before and after intervention to conduct a thematic review,and classify and statistically analyze the irrational use of antibiotics.Compare and observe the changes in antibacterial drug sales,DDDS,and DUI before and after intervention,as well as the incidence of irrational prescriptions.RESULTS After the intervention,the sales of the main antibacterial drugs were significantly lower than before the intervention,with a decrease of 4.72%.Among them,the sales of antibacterial drug injections decreased significantly,with a decrease of 10.07 percentage points in proportion.After intervention,the average intensity of antibacterial drug use was 45.26 DDDS,which was significantly lower than the 60.72 DDDS before intervention(P<0.01).After intervention,the average DUI of major antibacterial drug was 0.628,which was significantly lower than 0.938 before intervention(P<0.05).The problem and risk of irrational use of major antibiotics were significantly reduced.The incidence of unqualified prescription after intervention was significantly lower at 2.00%compared to 16.50%before intervention(P<0.05).CONCLUSION Clinical pharmacists have a significant pharmaceutical intervention effect on irrational use of antibiotics,which can effectively reduce the incidence of irrational use and the intensity of antibiotic use,and has significant application value.
作者
温伟添
简福梅
赵志斌
WEN Wei-tian;JIAN Fu-mei;ZHAO Zhi-bin(Department of Pharmacy,Longyan First Affiliated Hospital of Fujian Medical University,Longyan 364000,China)
出处
《海峡药学》
2025年第6期41-44,共4页
Strait Pharmaceutical Journal
基金
联合资金项目(龙岩)(编号:2023LYF17063)。
关键词
临床药师
抗菌药物
不合理用药
药学干预
效果
价值
Clinical Pharmacist
Antibacterial Drugs
Unreasonable Use of Drugs
Pharmaceutical Intervention
Effect
Value
