摘要
目的探讨老年轻度认知障碍(MCI)患者合并肌少症的相关因素及有效防治措施。方法回顾性分析2022年1月至2024年12月在我院就诊的70例老年MCI患者,根据患者是否合并肌少症分为对照组和合并组。对比两组患者人口学资料、营养状况、生活方式、骨骼肌含量与共病情况。采用Logistic回归分析筛选MCI合并肌少症的独立危险因素。结果70例MCI患者中,19例(27.14%)合并肌少症;单因素及多因素分析显示,年龄≥75岁、缺乏维生素D、高共病负担均是MCI患者合并肌少症的影响因素(P<0.05)。结论老年MCI患者合并肌少症与高龄、维生素D缺乏、高共病负担密切相关,早期综合干预可改善患者肌肉功能与认知结局,需采取多维度防治策略以延缓疾病进展。
Objective To investigate related factors and effective control measures of sarcopenia in elderly patients with mild cognitive impairment(MCI).Methods Seventy elderly patients with MCI who visited the hospital between January 2022 and December 2024 were reviewed.They were divided into the control group and the complication group according to whether they had sarcopenia.The demographic data,nutritional status,lifestyles,skeletal muscle content,and comorbidities were compared between the two groups.Logistic regression analysis was used to screen independent risk factors for MCI complicated with sarcopenia.Results Among the 70 patients with MCI,19 cases(27.14%)were complicated with sarcopenia.Univariate and multivariate analyses showed that age≥75 years,vitamin D deficiency,and high comorbidity burden were influencing factors of sarcopenia in patients with MCI(P<0.05).Conclusion Sarcopenia in elderly patients with MCI is closely related to advanced age,vitamin D deficiency,and high comorbidity burden.Early comprehensive intervention can improve patients'muscle function and cognitive outcomes.Therefore,multidimensional control measures should be taken to delay disease progression.
作者
张晨露
刘梦鸽
孙楠
ZHANG Chen-lu;LIU Meng-ge;SUN Nan(Department of Geriatrics,The First Affiliated Hospital of Henan University,Kaifeng 475000,Henan Province,China)
出处
《罕少疾病杂志》
2025年第7期27-29,共3页
Journal of Rare and Uncommon Diseases
基金
河南省医学科技攻关计划项目(LHGJ20220652)。
关键词
老年
轻度认知障碍
肌少症
因素
防治措施
Elderly
Mild Cognitive Impairment
Sarcopenia
Factor
Control Measure
