摘要
乳腺癌作为一种恶性肿瘤,严重危害全球女性健康,进展到晚期时死亡率往往较高,目前乳腺癌诊疗仍存在不足。不少学者对乳腺癌肿瘤微环境机制进行研究,并以此角度推行中医药防治乳腺癌,获得较多成果。乳腺癌属于“有形”之邪,肿瘤微环境的调控赖于阳气的推动,当“阳化气”不足,则易出现“阴性”病理产物,“阳化气,阴成形”与乳腺癌肿瘤微环境的关系密不可分。故本文以此为切入点阐述其对乳腺癌肿瘤微环境的影响,以期为中医药调控乳腺癌肿瘤微环境治疗原发病提供更有效的方法及研究思路。
Breast cancer,as a malignant tumor,poses a serious threat to women's health worldwide,with high mortality rates in advanced stages.Current diagnosis and treatment of breast cancer still have limitations.Many scholars have conducted research on the mechanisms of breast cancer tumor microenvironment(TME)and have achieved significant results in the prevention and treatment of breast cancer through Traditional Chinese Medicine(TCM)from this perspective.Breast cancer belongs to the category of“tangible”pathogenic factors,and the regulation of the tumor microenvironment relies on the propelling function of Yang Qi.When“Yang transforming Qi”becomes dysfunctional,it tends to produce“Yin-natured”pathological products.The relationship between“Yang transforming qi while yin constituting form”and the breast cancer tumor microenvironment is inseparable.Therefore,this article takes this perspective as an entry point to elaborate on its influence on the breast cancer tumor microenvironment,aiming to provide more effective methods and research ideas for TCM to regulate the breast cancer tumor microenvironment and treat the primary disease.
作者
王旸
杨瑞
史有阳
李斐斐
杨小娟
刘胜
WANG Yang;YANG Rui;SHI Youyang;LI Feifei;YANG Xiaojuan;LIU Sheng(Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine,Shanghai 200032,China;China Academy of Chinese Medical Sciences,Beijing 100700,China;Shanxi Tumor Hospital/Chinese Academy of Medical Sciences Cancer Hospital Shanxi Hospital/Shanxi Medical University Affiliated Cancer Hospital,Taiyuan 030013,China;Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)
出处
《中医药学报》
2025年第8期1-4,共4页
Acta Chinese Medicine and Pharmacology
基金
国家自然科学基金面上项目(82205132,82205114)。
关键词
乳腺癌
阳化气
阴成形
肿瘤微环境
理论探讨
Breast cancer
Yang transforming Qi
Yin constituting form
Tumor microenvironment
Theoretical exploration
