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2014—2023年吉林省丙型肝炎流行病学特征分析:基于Joinpoint回归模型

Epidemiological characteristics of hepatitis C in Jilin Province,2014-2023:based on Joinpoint regression model
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摘要 目的分析2014—2023年吉林省丙型肝炎的流行病学特征及趋势,为制定防控策略提供参考依据。方法对《中国疾病预防控制信息系统》中2014—2023年吉林省丙型肝炎疫情资料进行描述性流行病学分析;使用Joinpoint软件构建以年度为自变量、报告病例数/构成比为因变量的线性回归模型探索其流行趋势。结果2014—2023年吉林省累计报告丙型肝炎42212例,年报告病例数总体呈下降趋势(AAPC=-7.06%,P<0.05)。吉林省9个市(州)每年均有丙型肝炎病例报告,累计报告病例数排名前3位为长春市(9947例,占23.56%)、松原市(8039例,占19.04%)和吉林市(5386例,占12.76%)。除吉林市、通化市、梅河口市外,其他市(州)报告病例数总体均呈下降趋势(AAPC<0,P<0.05)。各市(州)回归结构各异,其中梅河口市2018年后呈上升趋势(APC=8.89%,P<0.05)。男女性别为1.11∶1,病例主要分布于≥50岁年龄段(34445例,占81.60%)。男性除10~岁组外,其他年龄组报告病例数总体呈下降趋势(AAPC<0,P<0.05);女性除10~岁组和70~岁组外,其他年龄组报告病例数总体呈下降趋势(AAPC<0,P<0.05),其中30~岁组2020年后呈快速上升趋势(APC=24.90%,P<0.05)。职业以农民为主(20430例,占48.40%)。结论2014—2023年吉林省丙型肝炎年报告病例数总体呈下降趋势,应重点关注近年发病呈上升趋势的梅河口市和≥30岁的女性,有针对性地开展丙型肝炎综合性防控工作。 Objective To analyze the epidemiological features of and trends in hepatitis C in Jilin Province from 2014 to 2023,and to provide a reference basis for formulating prevention and control strategies.Methods Descriptive epidemiological analysis was performed on the data about the hepatitis C epidemics in Jilin Province during 2014-2023 from the Chinese Information System for Disease Control and Prevention.Joinpoint software was used to construct a linear regression model with the year as the independent variable and the number of reported cases/composition ratio as the dependent variable for exploring the prevalence trend of hepatitis C.Results A total of 42,212 cases of hepatitis C were cumulatively reported in Jilin Province from 2014 to 2023,and the number of the annual reported cases showed an overall decreasing trend(AAPC=-7.06%,P<0.05).Hepatitis C cases were reported annually in 9 cities(prefectures)of Jilin Province,and the top three cities in terms of the cumulative number of reported cases were Changchun City(n=9,947,23.56%),Songyuan City(n=8,039,19.04%)and Jilin City(n=5,386,12.76%).The numbers of reported cases in all cities(prefectures)expect Jilin City,Tonghua City and Meihekou City generally showed downward trends(AAPC<0,P<0.05).The regression structure of each city(prefecture)was different,among which Meihekou City showed an upward trend after 2018(APC=8.89%,P<0.05).The male-to-female sex ratio was 1.11∶1.The cases were mainly distributed in the group aged≥50 years(n=34,445,81.60%).The numbers of reported cases in all male age groups except the male group aged 10-years generally showed downward trends(AAPC<0,P<0.05).The numbers of reported cases in all female age groups except the female group aged 10-and 70-years generally showed decreasing trends(AAPC<0,P<0.05),among which the number of reported cases in the female group aged 30-years showed a rapid upward trend after 2020(APC=24.90%,P<0.05).As for occupations,most of the reported cases were farmers(n=20,430,48.40%).Conclusion The annual reported cases of hepatitis C in Jilin Province during 2014-2023 showed an overall decreasing trend.Special attention should be paid to Meihekou City,where the incidence has shown an upward trend in recent years,and the females aged 30-years,and targeted comprehensive prevention and control measures against hepatitis C should be implemented.
作者 李娜 范吉祥 邱柏红 黄黎宁 李紫璇 吴丹 胡彦 LI Na;FAN Jixiang;QIU Baihong;HUANG Lining;LI Zixuan;WU Dan;HU Yan(Jilin Provincial Center for Disease Control and Prevention,Jilin Provincial Academy of Preventive Medicine,Changchun,Jilin 130062,China)
出处 《实用预防医学》 2025年第5期561-565,共5页 Practical Preventive Medicine
基金 吉林省卫生健康科技能力提升项目(2022GW006)。
关键词 丙型肝炎 流行病学 特征 Joinpoint回归 hepatitis C epidemiological characteristic Joinpoint regression
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