摘要
目的探讨老年缺血性脑血管病(ischemic cerebrovascular disease,ICD)患者治疗期间,阿司匹林肠溶片+颅内血管介入的应用效果。方法目的选取河池市人民医院于2022年1月—2023年12月收治的120例老年ICD患者为研究对象。根据治疗方式不同分为两组,各60例。对照组给予患者硫酸氢氯吡格雷、阿托伐他汀钙+血管介入治疗,观察组在颅内血管介入治疗的基础上,联合应用阿司匹林肠溶片治疗。比较两组治疗效果、动脉血管的收缩期峰值血流速度(peak systolic velocity,PSV)、血脂水平、美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)评分及并发症。结果观察组总有效率为100.00%(60/60),高于对照组的90.00%(54/60),差异有统计学意义(χ^(2)=4.386,P<0.05)。观察组动脉血管PSV、血脂水平、NIHSS评分均优于对照组,差异均有统计学意义(P均<0.05)。两组并发症相比,差异无统计学意义(P>0.05)。结论血管介入+阿司匹林肠溶片用于老年ICD患者能有效改善患者血脂水平,降低NIHSS评分,有效控制患者动脉PSV与不良反应。
Objective To explore the application effect of aspirin enteric-coated tablets+intracranial vascular intervention during the treatment of elderly patients with ischemic cerebrovascular disease(ICD).Methods A total of 120 cases of elderly ICD patients admitted to Hechi People's Hospital from January 2022 to December 2023 were purposefully selected as the study subjects.According to different treatment methods,they were divided into two groups,60 cases in each group.The control group was treated with clopidogrel hydrogen sulfate,atorvastatin calcium and vascular interventional therapy.The observation group was treated with aspirin enteric-coated tablets on the basis of intracranial vascular interventional therapy.The therapeutic effect,peak systolic velocity(PSV),blood lipid level,National Institute of Health Stroke Scale(NIHSS)score and complications were compared between the two groups.Results The total effective rate of the observation group was 100.00%(60/60),which was higher 90.00%(4/60)than control group,and the difference was statistically significant(χ^(2)=4.386,P<0.05).The arterial blood vessel PSV,blood lipid level and NIHSS score in the observation group were better than those in the control group,and the differences were statistically significant(all P<0.05).There was no significant difference in complications between the two groups(P>0.05).Conclusion Vascular intervention+aspirin enteric-coated tablets for elderly patients with ICD can effectively improve blood lipid levels,reduce NIHSS scores,and effectively control arterial PSV and adverse reactions.
作者
敖潇
韦仕荣
韦晓阳
黄德生
AO Xiao;WEI Shirong;WEI Xiaoyang;HUANG Desheng(Department of Neurology,Section One,People's Hospital of Hechi City,Hechi 547000,Guangxi Zhuang Autonomous)
出处
《系统医学》
2025年第10期121-125,共5页
Systems Medicine
关键词
老年缺血性脑血管病
颅内血管介入
阿司匹林肠溶片
疗效
并发症
Elderly ischemic cerebrovascular disease
Intracranial vascular intervention
Aspirin enteric-coated tablets
Curative effect
Complications
