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清金化痰汤加减治疗痰热郁肺型风温肺热病的临床疗效

Clinical efficacy of modified Qingjin Huatan decoction in treating Phlegm-heat obstructing the lung syndrome in patients with wind-warm lung-heat disease
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摘要 目的探讨清金化痰汤加减治疗痰热郁肺型风温肺热病患者的临床疗效。方法选取2021年1月至2024年1月南平市建阳中医院收治的80例痰热郁肺型风温肺热病患者作为研究对象,按照随机数字表法分为观察组与对照组,每组40例。对照组给予常规西药治疗,观察组在对照组基础上联合清金化痰汤加减治疗。比较两组临床疗效、治疗前后症状评分、症状消失时间、治疗前后炎症因子水平及安全性。结果观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗后,两组咳嗽、痰量、痰色症状积分均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。治疗后,观察组退热、止咳、湿啰音消失及肺部影像学吸收时间均短于对照组,差异有统计学意义(P<0.05)。治疗后,两组WBC、C反应蛋白、中性粒细胞百分比水平均低于治疗前,且观察组低于对照组,差异有统计学意义(P<0.05)。两组均未发生不良反应。结论在常规西药治疗基础上联合清金化痰汤加减治疗痰热郁肺型风湿肺热病临床疗效显著,可缩短患者退热、止咳及肺部影像学吸收时间,改善肺功能和炎症指标,且具有良好的安全性。 Objective To explore the clinical efficacy of modified Qingjin Huatan decoction in treating patients with Phlegm-heat obstructing the lung syndrome in wind-warm lung-heat disease.Methods A total of 80 patients with Phlegm-heat obstructing the lung syndrome of wind-warm lung-heat disease admitted to Nanping Jianyang Hospital of Traditional Chinese Medicine from January 2021 to January 2024 were selected as the research subjects,and they were divided into the observation group and the control group according to the random number table method,with 40 cases in each group.The control group received conventional Western medicine treatment,and the observation group was combined with modified Qingjin Huatan decoction treatment on the basis of the control group.Clinical efficacy,symptom scores before and after treatment,symptom recovery time,inflammatory markers before and after treatment,and treatment safety were compared between the two groups.Results The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After the treatment,the symptom scores of cough,sputum volume and sputum color of the two groups were lower than those before the treatment,and the observation group was lower than the control group,and the differences were statistically significant(P<0.05).The time for fever reduction,cough relief,disappearance of wet rural sounds and absorption by lung imaging in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).After treatment,the levels of WBC,C-reactive protein and percentage of neutrophils of the two groups were lower than those before treatment,and the observation group was lower than the control group,and the differences were statistically significant(P<0.05).No adverse reactions occurred in either group of patients.Conclusion On the basis of conventional Western medicine treatment,the modified Qingjin Huatan decoction combined with treatment of patients with wind-warmth lung-heat disease of Phlegm-heat obstructing the lung syndrome has significant effect,shorten the time for fever resolution,cough relief and pulmonary imaging absorption,improve lung function and inflammatory markers,and has good safety.
作者 吴理平 朱永萍 谢寒径 WU Liping;ZHU Yongping;XIE Hanjing(Department of Internal Medicine,Nanping Jianyang Hospital of Traditional Chinese Medicine,Nanping,Fujian,354200,China)
出处 《当代医学》 2025年第3期63-66,共4页 Contemporary Medicine
关键词 清金化痰汤加减 风温肺热病 痰热郁肺证 退热时间 肺部影像学 Modified Qingjin Huatan decoction Wind-warm lung-heat disease Phlegm-heat obstructing the lungs syndrome Duration of fever reduction Radiological absorption
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