摘要
目的:观察苯磺顺阿曲库铵(CIS)在宫腔镜手术中的应用效果。方法:选择2023年4月-2024年4月本院收治的宫腔镜手术患者,根据麻醉方案不同分为常规组(n=54,给予常规全身麻醉),联合组(n=56,在常规组基础上给予CIS联合丙泊酚)并同时执行精细化围麻醉期护理模式。比较插管条件优良率、应激反应、心率、平均动脉压(MAP)、麻醉起效时间、麻醉作用时间、残余肌松效应持续时间、拔管4个成串刺激(TOF)恢复时间、不良反应。结果:联合组的插管条件优良率(92.9%)高于常规组(79.6%),插管时、切皮时、拔管时皮质醇、去甲肾上腺素、心率、MAP均低于常规组,麻醉起效时间(2.27±0.53 min)、麻醉作用时间(36.53±8.74 min)均长于常规组(2.03±0.44 min、32.75±8.15 min),残余肌松效应持续时间(10.52±3.06 min)、拔管TOF恢复时间(59.24±10.45 min)均短于常规组(14.47±4.31 min、72.11±14.73 min),不良反应总发生率(1.8%)低于常规组(14.8%)(均P<0.05)。结论:CIS用于宫腔镜手术麻醉效果肯定,可改善插管条件,减轻应激反应、围拔管期残余肌松效应,利于稳定心率、MAP,且安全性较好。
Objective:To observe the application effect of cisatracurium besylate(CIS)for the muscle relaxation of patients during hysteroscopic surgery.Methods:The patients who admitted to the hospital for hysteroscopic surgery were collected and were divided into two groups based on the different anesthesia plans from April 2023 to April 2024.54 patients in the two groups received routine general anesthesia,while 56 patients in group B received CIS and propofol combined with the simultaneously implementing a refined perioperative nursing model additionally.The excellent rate of the intubation conditions,the stress reactions situation,the heart rate,the mean arterial pressure(MAP),the onset time and the duration of anesthesia,the duration of the peri-extubation residual muscle relaxation effect,the recovery time of the extubation train-of-four(TOF)and the adverse reactions rate of the patients were compared between group A and group B.Results:The excellent and good rate of the intubation conditions(92.9%)of the patients in group B was significantly higher than that(79.6%)of the patients in group A.The levels of cortisol and norepinephrine,and the values of heart rate and MAP of the patients in group B during intubation,at skin incision and at extubation were significantly lower than those of the patients in group A.The onset time of anesthesia(2.27±0.53 min)and the duration of the anesthesia effect(36.53±8.74 min)of the patients in group B were significantly longer than those(2.03±0.44 min and 32.75±8.15 min)of the patients in group A.The duration of residual neuromuscular blockade(10.52±3.06 min)and the recovery time of TOF extubation(59.24±10.45 min)of the patients in group B were significantly shorter than those(14.47±4.31 min and 72.11±14.73 min)of the patients in group A.The total incidence of adverse reactions(1.8%)of the patients in group A was significantly lower than that(14.8%)of the patients in group A(all P<0.o5).Conclusion:The CIS used in hysteroscopic surgery of the patients has the definite anesthetic effect,which can improve their intubation conditions,reduce their stress reactions and peri-extubation residual muscle relaxation effect and stabilize their heart rate and MAP,and with better safety.
作者
付倩
叶鹏飞
李倩倩
FU Qian;YE Pengfei;LI Qianqian(Taihe County People's Hospital,Fuyang,Anhui Province,236600)
出处
《中国计划生育学杂志》
2025年第6期1301-1305,共5页
Chinese Journal of Family Planning
关键词
宫腔镜手术
苯磺顺阿曲库铵
应激反应
围拔管期残余肌松效应
Hysteroscopic surgery
Cisatracurium besylate
Stress reaction
Peri-extubation residual muscle relaxation effect
