摘要
目的 探讨在宫外孕患者保守治疗中联合应用米非司酮与甲氨蝶呤的临床效果。方法 本次研究共纳入72例宫外孕患者,均从医院在2021年5月至2023年12月期间收治的宫外孕患者中选取。采用随机分组法将患者分入联合组(36例)和对照组(36例)。联合组治疗方案为米非司酮联合甲氨蝶呤,对照组治疗方案为甲氨蝶呤单药。比较两组治疗总有效率、各项指标恢复情况、生活质量和不良反应。结果 与对照组相比,联合组治疗总有效率、SF-36各项目评分均更高,盆腔包块消失时间、腹痛消失时间及月经复潮时间均更短,P<0.05。两组不良反应发生率比较,P>0.05。结论 米非司酮联合甲氨蝶呤保守治疗宫外孕疗效显著,不仅可促进患者各项指标改善,提升生活质量,还可避免不良反应。
Objective:To explore the clinical effect of mifepristone combined with methotrexate in conservative treatment of ectopic pregnancy.Methods:A total of 72 patients with ectopic pregnancy were included in this study,all of whom were selected from the patients with ectopic pregnancy treated in the hospital from May 2021 to December 2023.Patients were randomly divided into combined group(36 cases)and control group(36 cases).The combination group was treated with mifepristone combined with methotrexate,while the control group was treated with methotrexate alone.The total effective rate、recovery of various indexes、quality of life and adverse reactions were compared between the two groups.Results:Compared with the control group,the total effective rate and SF-36 scores of the combined group were higher,and the time of pelvic mass disappearance,abdominal pain disappearance and menstrual regain were shorter,P<50.05.The incidence of adverse reactions between the two groups was compared,P>0.05.Conclusion:Mifepristone combined with methotrexate is effective in the conservative treatment of ectopic pregnancy,which can not only promote the improvement of patients'indexes and improve their quality of life,but also avoid adverse reactions.
作者
邱翠芳
孙红娟
Qiu Cuifang;Sun Hongjuan(Obstetrics and Gynecology Department of Xinghua Second People's Hospital,Taizhou Jiangsu 225700,China;Jiangsu Taizhou Xinghua Traditional Chinese Medicine Hospital Obstetrics and Gynecology Department,Taizhou Jiangsu 225700,China)
出处
《生命科学仪器》
2025年第1期189-191,共3页
Life Science Instruments
关键词
米非司酮
甲氨蝶呤
保守治疗
宫外孕
Mifepristone
Methotrexate:Conservative treatment
Ectopic pregnancy
Clinical effects
